Evidence map›Paper›PMID 25201921›Full record

ArticleJournal of primary care & community health2015

Treatment outcomes among people living with HIV who are food insecure and prescribed antiretrovirals taken with food.

Seth C Kalichman, Christopher Washington, Tamar Grebler, Ginger Hoyt, Brandi Welles, Cindy Merely, Christopher Kegler, Moira O Kalichman, Chauncey Cherry

Open access · greenAbstract read
In one paragraph

Article in Journal of primary care & community health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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  8. Food Insecurity and Unmet Needs Among Youth and Young Adults Living With HIV in the San Francisco Bay Area.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Seth C KalichmanUniversity of Connecticut, Storrs, CT, USA seth.k@uconn.edu.
Christopher WashingtonUniversity of Connecticut, Storrs, CT, USA.
Tamar GreblerUniversity of Connecticut, Storrs, CT, USA.
Ginger HoytUniversity of Connecticut, Storrs, CT, USA.
Brandi WellesUniversity of Connecticut, Storrs, CT, USA.
Cindy MerelyUniversity of Connecticut, Storrs, CT, USA.
Christopher KeglerUniversity of Connecticut, Storrs, CT, USA.
Moira O KalichmanUniversity of Connecticut, Storrs, CT, USA.
Chauncey CherryUniversity of Connecticut, Storrs, CT, USA.
University of Connecticut · US

Funding

Behavioral Intervention to Enhance HIV Test/TreatR01DA033067 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2012 to 2016
$3.3M
Neurochemical Sequelae of Prenatal MDMAR01DA017399 · NIDA · UNIVERSITY OF CINCINNATI · PI LIPTON, JACK WILLIAM · 2005 to 2009
$1.4M
Influence of Food Insecurity on AdherenceR01AA021471 · NIAAA · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2013 to 2015
$941k
NIAAA NIH HHS R01 AA021471NIAAA NIH HHS R01-AA021471NIDA NIH HHS R01 DA017399NIDA NIH HHS R01-DA017399NIDA NIH HHS R01 DA033067
6 · The paper itself

Abstract

backgroundFood insecurity is a known barrier to medication adherence among people living with HIV. Antiretroviral therapies (ART) that require food likely pose added challenges to patients who do not have reliable access to food. This study examines the health implications of prescribing ART that requires food to patients who are food insecure.

methodA community sample of 538 men and 221 women currently taking ART to treat their HIV infection completed computerized interviews, biweekly unannounced pill count adherence assessments, and obtained their HIV RNA (viral load) and CD4 cell count from medical records.

resultsSixty-three percent of participants experienced at least 1 indicator of food insecurity during the previous month, of which 274 (57%) were prescribed an ART regimen that requires food. Among participants who were food insecure, individuals taking ART requiring food indicated significantly greater HIV symptoms, had lower CD4 cell counts, and poorer HIV suppression. For participants who were food secure, those taking ART that requires food were significantly less adherent than those whose ART regimen does not require food.

conclusionsPeople living with HIV who experience food insecurity are significantly more likely to be prescribed ART regimens that require food and experience poorer treatment outcomes. Determination of optimal ART regimens should take patient access to food into account and treatment guidelines should explicitly highlight the importance of food access in selecting ART regimens.

Indexed as

Antiretroviral Therapy, Highly ActiveDrug PrescriptionsFoodFood SupplyMedication AdherenceAdultAnti-HIV AgentsCD4 Lymphocyte CountFemaleHIVHIV InfectionsHumansMaleSeverity of Illness IndexTreatment OutcomeViral LoadAnti-HIV Agentsdisease managementhealth outcomeshealth promotionmedicationsprimary care

Identifiers

PMID25201921
PMCPMC4293697
OpenAlexW2024568269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.