ArticlePlant physiology2014
Evolutionary conserved function of barley and Arabidopsis 3-KETOACYL-CoA SYNTHASES in providing wax signals for germination of powdery mildew fungi.
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Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 91 citations in OpenAlex.
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- A GDSL-motif Esterase/Lipase Affects Wax and Cutin Deposition and Controls Hull-Caryopsis Attachment in Barley.Plant & cell physiology · 2024Article
- Beyond skin-deep: targeting the plant surface for crop improvement.Journal of experimental botany · 2023Review
- Biosynthesis of barley wax β-diketones: a type-III polyketide synthase condensing two fatty acyl units.Nature communications · 2023Article
- Multiomics analysis reveals the molecular mechanisms underlying virulence in Rhizoctonia and jasmonic acid-mediated resistance in Tartary buckwheat (Fagopyrum tataricum).The Plant cell · 2023Article
- WAX INDUCER 1 Regulates β-Diketone Biosynthesis by Mediating Expression of theInternational journal of molecular sciences · 2023Article
- Germination Development of Powdery Mildew on Natural and Artificial Wheat Leaf Surfaces: A Study to Investigate Plant Wax Signals.Small science · 2023Article
- Pathogen Resistance Depending on Jacalin-Dirigent Chimeric Proteins Is Common among Poaceae but Absent in the Dicot Arabidopsis as Evidenced by Analysis of Homologous Single-Domain Proteins.Plants (Basel, Switzerland) · 2022Article
- Transcriptome Analysis Reveals a Comprehensive Virus Resistance Response Mechanism in Pecan Infected by a Novel Badnavirus Pecan Virus.International journal of molecular sciences · 2022Article
- Characterization of Glossy Spike Mutants and Identification of Candidate Genes Regulating Cuticular Wax Synthesis in Barley (International journal of molecular sciences · 2022Article
- Conserved signalling components coordinate epidermal patterning and cuticle deposition in barley.Nature communications · 2022Article
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- Transcriptional regulation of KCS gene by bZIP29 and MYB70 transcription factors during ABA-stimulated wound suberization of kiwifruit (Actinidia deliciosa).BMC plant biology · 2022Article
- Exploring and exploiting cuticle biosynthesis for abiotic and biotic stress tolerance in wheat and barley.Frontiers in plant science · 2022Review
- Toward a smart skin: Harnessing cuticle biosynthesis for crop adaptation to drought, salinity, temperature, and ultraviolet stress.Frontiers in plant science · 2022Review
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Authors and funding
13 authors at 6 institutions in 2 countries.
Denise WeidenbachDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Marcus JansenDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Rochus B FrankeDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Goetz HenselDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Wiebke WeissgerberDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Sylvia UlfertsDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Irina JansenDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Lukas SchreiberDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Viktor KorzunDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Rolf PontzenDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Jochen KumlehnDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Klaus PillenDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.).
Ulrich SchaffrathDepartment of Plant Physiology, Rheinisch-Westfaelische Technische Hochschule Aachen University, D-52056 Aachen, Germany (D.W., M.J., S.U., I.J., U.S.);Institute of Biosciences and Geosciences: Plant Sciences, Juelich Plant Phenotyping Centre, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany (M.J.);Ecophysiology of Plants, Institute of Cellular and Molecular Botany, University of Bonn, 53115 Bonn, Germany (R.B.F., L.S.);Plant Reproductive Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Stadt Seeland/OT Gatersleben, Germany (G.H., J.K.);Institute of Agricultural and Nutritional Sciences, Chair of Plant Breeding, Martin Luther University Halle-Wittenberg, 06120 Halle/Saale, Germany (W.W., K.P.); Cereals Biotechnology,KWS LOCHOW GMBH, 37574 Einbeck, Germany (V.K.); andFormulation Technology, Bayer CropScience AG, 40789 Manheim, Germany (R.P.) schaffrath@bio3.rwth-aachen.de.
Cereal Research (Hungary) · HULeibniz Institute of Plant Genetics and Crop Plant Research · DEUniversity of Bonn · DEBayer (Germany) · DEForschungszentrum Jülich · DEKWS Saat (Germany) · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
For plant pathogenic fungi, such as powdery mildews, that survive only on a limited number of host plant species, it is a matter of vital importance that their spores sense that they landed on the right spot to initiate germination as quickly as possible. We investigated a barley (Hordeum vulgare) mutant with reduced epicuticular leaf waxes on which spores of adapted and nonadapted powdery mildew fungi showed reduced germination. The barley gene responsible for the mutant wax phenotype was cloned in a forward genetic screen and identified to encode a 3-KETOACYL-CoA SYNTHASE (HvKCS6), a protein participating in fatty acid elongation and required for synthesis of epicuticular waxes. Gas chromatography-mass spectrometry analysis revealed that the mutant has significantly fewer aliphatic wax constituents with a chain length above C-24. Complementation of the mutant restored wild-type wax and overcame germination penalty, indicating that wax constituents less present on the mutant are a crucial clue for spore germination. Investigation of Arabidopsis (Arabidopsis thaliana) transgenic plants with sense silencing of Arabidopsis REQUIRED FOR CUTICULAR WAX PRODUCTION1, the HvKCS6 ortholog, revealed the same germination phenotype against adapted and nonadapted powdery mildew fungi. Our findings hint to an evolutionary conserved mechanism for sensing of plant surfaces among distantly related powdery mildews that is based on KCS6-derived wax components. Perception of such a signal must have been evolved before the monocot-dicot split took place approximately 150 million years ago.
Indexed as
3-Oxoacyl-(Acyl-Carrier-Protein) SynthaseAcyltransferasesArabidopsisArabidopsis ProteinsAscomycotaBiological EvolutionGene Expression Regulation, PlantHordeumHost-Pathogen InteractionsMutationPlant DiseasesPlant ProteinsPlants, Genetically ModifiedSpores, FungalWaxes3-ketoacyl-CoA synthase, Arabidopsis3-Oxoacyl-(Acyl-Carrier-Protein) SynthaseAcyltransferasesArabidopsis ProteinsCUT1 protein, ArabidopsisPlant ProteinsWaxes
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