ReviewNeurobiology of disease2015
Restoring tactile and proprioceptive sensation through a brain interface.
Review in Neurobiology of disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 82 citations in OpenAlex.
- Visual context affects the perceived timing of tactile sensations elicited through intracortical microstimulation: a case study of two participants.Journal of neurophysiology · 2025Article
- A worldwide research overview of Artificial Proprioception in prosthetics.PLOS digital health · 2025Review
- The Next Frontier in Neuroprosthetics: Integration of Biomimetic Somatosensory Feedback.Biomimetics (Basel, Switzerland) · 2025Review
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Visual context affects the perceived timing of tactile sensations elicited through intra-cortical microstimulation.bioRxiv : the preprint server for biology · 2024Article
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.bioRxiv : the preprint server for biology · 2024Article
- Article
- Favoring the cognitive-motor process in the closed-loop of BCI mediated post stroke motor function recovery: challenges and approaches.Frontiers in neurorobotics · 2023Review
- Understanding and Measuring the Cognitive Load of Amputees for Rehabilitation and Prosthesis Development.Archives of rehabilitation research and clinical translation · 2022Review
- Importance of Osseoperception and Tactile Sensibility during Masticatory Function in Different Prosthetic Rehabilitations: A Review.Medicina (Kaunas, Lithuania) · 2022Review
- Utility and lower limits of frequency detection in surface electrode stimulation for somatosensory brain-computer interface in humans.Neurosurgical focus · 2020Article
- Neural Representation of Observed, Imagined, and Attempted Grasping Force in Motor Cortex of Individuals with Chronic Tetraplegia.Scientific reports · 2020Article
- Restoring Somatosensation: Advantages and Current Limitations of Targeting the Brainstem Dorsal Column Nuclei Complex.Frontiers in neuroscience · 2020Article
- Selectivity of afferent microstimulation at the DRG using epineural and penetrating electrode arrays.Journal of neural engineering · 2019Article
- Neural correlates of proprioceptive upper limb position matching.Human brain mapping · 2019Article
- Functional Frequency Discrimination From Cortical Somatosensory Stimulation in Humans.Frontiers in neuroscience · 2019Article
- Evidence of Hyperacusis in Adult Rats Following Non-traumatic Sound Exposure.Frontiers in systems neuroscience · 2019Article
- Neural Basis of Touch and Proprioception in Primate Cortex.Comprehensive Physiology · 2018Review
- Automatic hand phantom map generation and detection using decomposition support vector machines.Biomedical engineering online · 2018Article
- Engineered Axonal Tracts as "Living Electrodes" for Synaptic-Based Modulation of Neural Circuitry.Advanced functional materials · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Somatosensation plays a critical role in the dexterous manipulation of objects, in emotional communication, and in the embodiment of our limbs. For upper-limb neuroprostheses to be adopted by prospective users, prosthetic limbs will thus need to provide sensory information about the position of the limb in space and about objects grasped in the hand. One approach to restoring touch and proprioception consists of electrically stimulating neurons in somatosensory cortex in the hopes of eliciting meaningful sensations to support the dexterous use of the hands, promote their embodiment, and perhaps even restore the affective dimension of touch. In this review, we discuss the importance of touch and proprioception in everyday life, then describe approaches to providing artificial somatosensory feedback through intracortical microstimulation (ICMS). We explore the importance of biomimicry--the elicitation of naturalistic patterns of neuronal activation--and that of adaptation--the brain's ability to adapt to novel sensory input, and argue that both biomimicry and adaptation will play a critical role in the artificial restoration of somatosensation. We also propose that the documented re-organization that occurs after injury does not pose a significant obstacle to brain interfaces. While still at an early stage of development, sensory restoration is a critical step in transitioning upper-limb neuroprostheses from the laboratory to the clinic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.