Evidence map›Paper›PMID 25201448›Full record

Observational studyBMC musculoskeletal disorders2014

Prediction of poor outcomes six months following total knee arthroplasty in patients awaiting surgery.

Eugen Lungu, François Desmeules, Clermont E Dionne, Etienne L Belzile, Pascal-André Vendittoli

4 registry-linked trialsAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC musculoskeletal disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02294890 unknown statusnot on this mapstarted 2015, after this paper: background citation

Does Fibrosis Diathesis Influence the Recovery of Knee Mobility After Total Knee Replacement?

TypeobservationalSponsorUniversity Hospital PellenbergRan2015 to 2015Enrolled60ConditionsKnee Replacement Arthroplasty, Fibrosis, Dupuytren's DiseaseArmsTotal knee arthroplasty
NCT02998125 completednot on this mapstarted 2017, after this paper: background citation

A Psychometric Analysis of the Arabic Version of Oxford Knee Score Before and After Total Knee Arthroplasty in a Middle East Population and an Exploration of Outcomes Post-total Knee Arthroplasty in the Middle East

TypeobservationalSponsorUniversity of SalfordRan2017 to 2020Enrolled116ConditionsTotal Knee ArthroplastyArmsTotal knee arthroplasty
NCT03132064 suspendednot on this mapstarted 2020, after this paper: background citation

The Association Between Pre-operative Pain Psychology and Hypersensitivity With Poor Functional Outcome After Knee Replacement

TypeobservationalSponsorUniversity of SalfordRan2020 to 2022Enrolled50ConditionsOutcome After Total Knee ArthroplastyArmstotal knee arthroplasty
NCT03132077 completednot on this mapstarted 2017, after this paper: background citation

Retrospective Analysis of Patient Outcome Questionnaire Following Primary Knee Replacement

TypeobservationalSponsorUniversity of SalfordRan2017 to 2020Enrolled1,301ConditionsTotal Knee ArthroplastyArmstotal knee arthroplasty
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Improved total knee arthroplasty pain outcome when joint gap targets are achieved throughout flexion.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Patient dissatisfaction following total knee arthroplasty: external validation of a new prediction model.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eugen Lungu
François DesmeulesOrthopaedic Clinical Research Unit, Maisonneuve-Rosemont Hospital University of Montreal affiliated Research Center, CP 6128 Succursale Centre-Ville, Montréal H3C 3 J7 Quebec, Canada. f.desmeules@umontreal.ca.
Clermont E Dionne
Etienne L Belzile
Pascal-André Vendittoli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentification of patients experiencing poor outcomes following total knee arthroplasty (TKA) before the intervention could allow better case selection, patient preparation and, likely, improved outcomes. The objective was to develop a preliminary prediction rule (PR) to identify patients enrolled on surgical wait lists who are at the greatest risk of poor outcomes 6 months after TKA.

methods141 patients scheduled for TKA were recruited prospectively from the wait lists of 3 hospitals in Quebec City, Canada. Knee pain, stiffness and function were measured 6 months after TKA with the Western Ontario and McMaster Osteoarthritis Index (WOMAC) and participants in the lowest quintile for the WOMAC total score were considered to have a poor outcome. Several variables measured at enrolment on the wait lists (baseline) were considered potential predictors: demographic, socioeconomic, psychosocial, and clinical factors including pain, stiffness and functional status measured with the WOMAC. The prediction rule was built with recursive partitioning.

resultsThe best prediction was provided by 5 items of the baseline WOMAC. The rule had a sensitivity of 82.1% (95% CI: 66.7-95.8), a specificity of 71.7% (95% CI: 62.8-79.8), a positive predictive value of 41.8% (95% CI: 29.7-55.0), a negative predictive value of 94.2% (95% CI: 87.1-97.5) and positive and negative likelihood ratios of 2.9 (95% CI: 1.8-4.7) and 0.3 (95% CI: 0.1-0.6) respectively.

conclusionsThe developed PR is a promising tool to identify patients at risk of worse outcomes 6 months after TKA as it could help improve the management of these patients. Further validation of this rule is however warranted before clinical use.

Indexed as

Waiting ListsAgedArthroplasty, Replacement, KneeCohort StudiesFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedOsteoarthritis, KneePredictive Value of TestsProspective StudiesTime FactorsTreatment Outcome

Identifiers

PMID25201448
PMCPMC4247215

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.