ReviewCurrent psychiatry reports2014
Genetics of schizophrenia.
Review in Current psychiatry reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Long-term neurodevelopmental consequences of intrauterine exposure to lithium and antipsychotics: a systematic review and meta-analysis.European child & adolescent psychiatry · 2018Pooled it
- Sleep disturbances as an early indicator of psychotic disorders in adolescents and young adults.Frontiers in synaptic neuroscience · 2026Review
- Calcium Signalling in Neurological Disorders, with Insights from Miniature Fluorescence Microscopy.Cells · 2024Review
- Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.Molecular psychiatry · 2024Article
- Dopaminergic Epistases in Schizophrenia.Brain sciences · 2024Review
- Optimising the use of electronic medical records for large scale research in psychiatry.Translational psychiatry · 2024Review
- A Holistic Approach to Cardiopulmonary Concerns in a Schizophrenic Patient and Ensuring Quality Care.Cureus · 2023Article
- Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits.Advances in drug and alcohol research · 2023Review
- Cellular Models in Schizophrenia Research.International journal of molecular sciences · 2021Review
- The Importance of Patient-Centered Care in Colon Cancer Patients With Severe Mental Illness.Cureus · 2021Article
- Clozapine Response for Vocal Tics in Schizophrenic Patients: A Case Report With Literature Review.Cureus · 2021Article
- Oxidative Stress-Related Mechanisms in Schizophrenia Pathogenesis and New Treatment Perspectives.Oxidative medicine and cellular longevity · 2021Review
- Article
- Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons.The EMBO journal · 2018Article
- Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice.Scientific reports · 2018Article
- 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish.PloS one · 2018Article
- Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.Journal of molecular neuroscience : MN · 2018Article
- Upregulation of vitamin D-related genes in schizophrenic patients.Neuropsychiatric disease and treatment · 2018Article
- Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.Journal of neuroscience research · 2017Review
- The roots of empathy: Through the lens of rodent models.Neuroscience and biobehavioral reviews · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet recent studies, especially in the past year, have confirmed genetics as the major cause of this complex condition. Psychiatry has come of age: it is perhaps more difficult for the current generation of psychiatrists, to comprehend how the biological root of the condition could have been denied for so long. Here we review how highly collaborative global efforts to pool samples, utilise the very latest advances in genotyping and high throughput sequencing technologies, and application of robust statistical analysis have reaped phenomenal rewards. The major findings are that schizophrenia is a highly polygenic disorder with a complex array of risk loci, many include genes implicated also in intellectual disability, autism spectrum disorders, bipolar disorder and major depressive disorder. These candidate genes converge on key neuronal signalling pathways identifying novel targets for potential future therapeutic intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.