ArticleThe American journal of tropical medicine and hygiene2014
Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Prevalence of Respiratory Pathogens in Nasopharyngeal Swabs of Febrile Patients with or without Respiratory Symptoms in the Niakhar Area of Rural Senegal.Pathogens (Basel, Switzerland) · 2024Article
- Aetiologies of bacterial tick-borne febrile illnesses in humans in Africa: diagnostic limitations and the need for improvement.Frontiers in medicine · 2024Review
- Development of a New Genus-Specific Quantitative Real-Time PCR Assay for the Diagnosis of Scrub Typhus in South America.Frontiers in medicine · 2022Article
- Neglected human Rickettsia felis infection in Taiwan: A retrospective seroepidemiological survey of patients with suspected rickettsioses.PLoS neglected tropical diseases · 2021Article
- Manifestations and Management of Flea-Borne Rickettsioses.Research and reports in tropical medicine · 2021Review
- Rickettsia felis identified in two fatal cases of acute meningoencephalitis.PLoS neglected tropical diseases · 2020Article
- High Circulation of Malaria and Low Prevalence of Bacteremia in Febrile and Afebrile Children in Northeastern Gabon.The American journal of tropical medicine and hygiene · 2020Article
- Asymptomatic carriage of Streptococcus pneumoniae detected by qPCR on the palm of hands of populations in rural Senegal.PLoS neglected tropical diseases · 2018Article
- Emerging infectious diseases in Africa in the 21st century.New microbes and new infections · 2018Review
- Serum cytokine responses in Rickettsia felis infected febrile children, Ghana.Medical microbiology and immunology · 2018Article
- Rickettsial Illnesses as Important Causes of Febrile Illness in Chittagong, Bangladesh.Emerging infectious diseases · 2018Article
- Nationwide prevalence ofNew microbes and new infections · 2017Article
- Effect of Rickettsia felis Strain Variation on Infection, Transmission, and Fitness in the Cat Flea (Siphonaptera: Pulicidae).Journal of medical entomology · 2017Article
- Article
- Flea-Borne Rickettsioses and Rickettsiae.The American journal of tropical medicine and hygiene · 2017Review
- The Point-of-Care Laboratory in Clinical Microbiology.Clinical microbiology reviews · 2016Review
- Transmission mechanisms of an emerging insect-borne rickettsial pathogen.Parasites & vectors · 2016Article
- Reply to Slesak et al.: So much about Rickettsia felis infection to be discovered.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Possible Role of Rickettsia felis in Acute Febrile Illness among Children in Gabon.Emerging infectious diseases · 2015Article
- Molecular Detection of Fastidious and Common Bacteria as Well as Plasmodium spp. in Febrile and Afebrile Children in Franceville, Gabon.The American journal of tropical medicine and hygiene · 2015Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fever caused by Rickettsia felis was recently shown to play an important role in infectious diseases morbidity in sub-Saharan Africa. We collected 68 cotton swabs from fever-associated eschars in four different regions of Senegal. In 5 of 68 eschar samples (7.4%), we have identified DNA from R. felis. In 49 of 68 eschar samples (72.1%), we have identified DNA from Staphylococcus aureus. In 35 of 68 eschar samples (51.5%), we have identified DNA from Streptococcus pyogenes, and in 4 of 68 eschar samples (5.9%), we have identified DNA from Streptococcus pneumoniae. In 34 cases, S. aureus was found together with S. pyogenes. DNA from R. felis was also found in swabs from the skin of the healthy Senegalese villagers (3 of 60; 5%) but not French urbanites. The presence of S. aureus and S. pyogenes was significantly associated with the presence of eschars in febrile patients compared with the healthy skin from the control group. Finally, we confirmed that Senegal is an endemic region for R. felis, which is found in both eschars and healthy skin swabs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.