ReviewMammalian genome : official journal of the International Mammalian Genome Society2014
A review of standardized metabolic phenotyping of animal models.
Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Aminoadipate-semialdehyde synthase, a potential target for substrate reduction therapy in glutaric aciduria type 1.Scientific reports · 2026Article
- Loss of histone macroH2A1.1 causes kidney abnormalities secondary to a change in nutrient metabolization.Science advances · 2025Article
- Arduino allows development of a low-cost, high-resolution metabolic and behavioral phenotyping system for birds.The Journal of experimental biology · 2025Article
- A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.Sleep · 2024Article
- Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria.Human molecular genetics · 2023Article
- Infection-elicited microbiota promotes host adaptation to nutrient restriction.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Adipose MDM2 regulates systemic insulin sensitivity.Scientific reports · 2021Article
- Modulating the Metabolic Phenotype of Cancer Microenvironment.Advances in experimental medicine and biology · 2020Review
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.Molecular neurobiology · 2017Article
- Body Temperature Measurements for Metabolic Phenotyping in Mice.Frontiers in physiology · 2017Article
- The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.G3 (Bethesda, Md.) · 2016Article
- Article
- Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.PloS one · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic phenotyping of genetically modified animals aims to detect new candidate genes and related metabolic pathways that result in dysfunctional energy balance regulation and predispose for diseases such as obesity or type 2 diabetes mellitus. In this review, we provide a comprehensive overview on the technologies available to monitor energy flux (food uptake, bomb calorimetry of feces and food, and indirect calorimetry) and body composition (qNMR, DXA, and MRI) in animal models for human diseases with a special focus on phenotyping methods established in genetically engineered mice. We use an energy flux model to illustrate the principles of energy allocation, describe methodological aspects how to monitor energy balance, and introduce strategies for data analysis and presentation.
Indexed as
Identifiers
25199945What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.