ReviewSchmerz (Berlin, Germany)2014
[Metamizole (dipyrone): mode of action, drug-drug interactions, and risk of agranulocytosis].
Review in Schmerz (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for treatment of acute pain in children - the consensus statement of the Section of Paediatric Anaesthesiology and Intensive Therapy of the Polish Society of Anaesthesiology and Intensive Therapy.Anaesthesiology intensive therapy · 2022Guideline
- Drug interactions in patients with alcohol use disorder: results from a real-world study on an addiction-specific ward.Therapeutic advances in drug safety · 2025Article
- Isolated Severe Neutropenia in Adults, Evaluation of Underlying Causes and Outcomes, Real-World Data Collected over a 5-Year Period in a Tertiary Referral Hospital.Medicina (Kaunas, Lithuania) · 2024Article
- Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose.Drugs in R&D · 2023Article
- News in pharmacology for the main medical pathologies of gestation.Frontiers in pharmacology · 2023Review
- Pain management in hemophilia: expert recommendations.Wiener klinische Wochenschrift · 2021Review
- COVID-19: Pain Management in Patients with SARS-CoV-2 Infection-Molecular Mechanisms, Challenges, and Perspectives.Brain sciences · 2020Article
- [Considerations concerning the perioperative use of metamizole].Der Anaesthesist · 2019Review
- Impact of drugs on venous thromboembolism risk in surgical patients.European journal of clinical pharmacology · 2019Review
- [Pharmacology of non-opioid analgesics].Schmerz (Berlin, Germany) · 2019Article
- [Pain therapy for children and adolescents with hemophilia : Recommendations by an expert panel].Schmerz (Berlin, Germany) · 2018Review
- The Conservative Treatment of Traumatic Thoracolumbar Vertebral Fractures.Deutsches Arzteblatt international · 2018Review
- Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1.BMC pharmacology & toxicology · 2017Article
- [Side effects of pain therapy : Sufficient analgesia without unnecessary complications].Der Urologe. Ausg. A · 2017Article
- [Metamizole].Schmerz (Berlin, Germany) · 2015Article
- Metamizole versus placebo for panretinal photocoagulation pain control: a prospective double-masked randomized controlled study.International journal of retina and vitreous · 2015Article
Corrections and comments
- Commented on by[Metamizole].2015
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metamizole (dipyrone) is a nonsteroidal compound with strong analgesic as well as antipyretic and spasmolytic properties. Based on a small number of cases of agranulocytosis, metamizole was withdrawn from the market in some countries. Other countries restricted its use. This paper discusses the safety aspects of metamizole and compares it with other compounds used for similar indications.
Indexed as
Identifiers
25199942What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.