Evidence map›Paper›PMID 25199642›Full record

ArticleArthritis & rheumatology (Hoboken, N.J.)2014

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus.

Elena López-Isac, Lara Bossini-Castillo, Sandra G Guerra, Christopher Denton, Carmen Fonseca, Shervin Assassi, Xiaodong Zhou, Maureen D Mayes, Carmen Pilar Simeón, Norberto Ortego-Centeno and 21 more

Abstract read
In one paragraph

Article in Arthritis & rheumatology (Hoboken, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Transethnic meta-analysis identifiesAnnals of the rheumatic diseases · 2017
    Pooled it
  3. Pooled it
  4. Association ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Updates on genetics in systemic sclerosis.Inflammation and regeneration · 2021
    Review
  10. Genetics of systemic sclerosis.Journal of scleroderma and related disorders · 2020
    Review
  11. Review
  12. Review
  13. Genetics of systemic sclerosis: recent advances.Current opinion in rheumatology · 2015
    Review
  14. Genetics of systemic sclerosis.Seminars in immunopathology · 2015
    Review
  15. Article
  16. Review
  17. Pathogenesis of Systemic Sclerosis.Frontiers in immunology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Elena López-IsacInstitute of Parasitology and Biomedicine, López-Neyra, Consejo Superior de Investigaciones Cientificas and Parque Tecnologico de la Salud, Granada, Spain.
Lara Bossini-Castillo
Sandra G Guerra
Christopher Denton
Carmen Fonseca
Shervin Assassi
Xiaodong Zhou
Maureen D Mayes
Carmen Pilar Simeón
Norberto Ortego-Centeno
Iván Castellví
Patricia Carreira
Spanish Scleroderma Group
Olga Gorlova
Lorenzo Beretta
Alessandro Santaniello
Claudio Lunardi
Roger Hesselstrand
Annika Nordin
Gabriela Riemekasten
Torsten Witte
Nicolas Hunzelmann
Alexander Kreuter
Jörg H W Distler
Alexandre E Voskuyl
Jeska de Vries-Bouwstra
Bobby P Koeleman
Ariane Herrick
Jane Worthington
Timothy R D J Radstake
Javier Martin

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Role of TGF-beta and CTGF Signaling Transgenic Mouse Models of SclerodermaP50AR054144 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAN, FILEMON K. · 2006 to 2010
$7.7M
CTSA: K12 COMPONENTKL2RR024149 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2011
$6.7M
Two-Stage Genome-Wide Association Study in Systemic SclerosisR01AR055258 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MAYES, MAUREEN MAUREEN · 2008 to 2012
$5.9M
Studies of HLA Region Genomics in Systemic Sclerosis and Ankylosing SpondyilitisU01AI090909 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MAYES, MAUREEN MAUREEN, REVEILLE, JOHN DUFFIN · 2010 to 2014
$2.9M
SCLERODERMA FAMILY REGISTRY AND DNA REPOSITORY-264002251-264002251-264002251N01AR002251 · NIAMS · WAYNE STATE UNIVERSITY · PI MAYES, MAUREEN · 2000 to 2006
$659k
Molecular Markers for Progression of Pulmonary Fibrosis in Systemic SclerosisK23AR061436 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ASSASSI, SHERVIN · 2011 to 2014
$494k
NCATS NIH HHS UL1 TR000371NCRR NIH HHS 3UL1-RR-024148NCRR NIH HHS KL2 RR024149NCRR NIH HHS KL2-RR-024149-04NCRR NIH HHS UL1 RR024148NIAID NIH HHS U01-1U01-AI09090NIAID NIH HHS U01 AI090909NIAMS NIH HHS K23 AR061436NIAMS NIH HHS K23-AR-061436NIAMS NIH HHS N01 AR002251NIAMS NIH HHS N01-AR-0-2251NIAMS NIH HHS P50 AR054144NIAMS NIH HHS P50-AR-054144NIAMS NIH HHS R01 AR055258NIAMS NIH HHS R01-AR-055258
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Case-Control StudiesGene FrequencyGenetic Predisposition to DiseaseHumansLogistic ModelsPolymorphism, Single NucleotideReceptors, Interleukin-12Scleroderma, SystemicIL12RB1 protein, humanReceptors, Interleukin-12

Identifiers

PMID25199642
PMCPMC4245383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.