Trial reportPloS one2014
Natural history of cutaneous human papillomavirus (HPV) infection in men: the HIM study.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 83 citations in OpenAlex.
- Review
- Role of non-coding RNAs in human-papillomavirus-associated cutaneous neoplasms.Archives of virology · 2025Review
- Article
- Compromised T Cell Immunity Links Increased Cutaneous Papillomavirus Activity to Squamous Cell Carcinoma Risk.JID innovations : skin science from molecules to population health · 2023Article
- Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections.The Journal of infectious diseases · 2022Article
- Spaceflight Virology: What Do We Know about Viral Threats in the Spaceflight Environment?Astrobiology · 2022Review
- Seroprevalence of mucosal and cutaneous human papillomavirus (HPV) types among children and adolescents in the general population in Germany.BMC infectious diseases · 2022Article
- Cutaneous viral infections associated with ultraviolet radiation exposure.International journal of cancer · 2021Article
- β-HPV 8E6 combined with TERT expression promotes long-term proliferation and genome instability after cytokinesis failure.Virology · 2020Article
- The Pathobiology of Skin Aging: New Insights into an Old Dilemma.The American journal of pathology · 2020Review
- Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women.Infectious agents and cancer · 2020Article
- Viruses in Skin Cancer (VIRUSCAN): Study Design and Baseline Characteristics of a Prospective Clinic-Based Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- Cross-sectional associations between cutaneous viral infections and regulatory T lymphocytes in circulation.The British journal of dermatology · 2019Article
- Keratinocyte Carcinomas: Current Concepts and Future Research Priorities.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019Review
- An Emerging Issue in Oncogenic Virology: the Role of Beta Human Papillomavirus Types in the Development of Cutaneous Squamous Cell Carcinoma.Journal of virology · 2019Review
- Prevalence and Correlates of β- and γ-Human Papillomavirus Detection in Oral Samples From Mid-Adult Women.The Journal of infectious diseases · 2019Article
- Cutaneous Viral Infections Across 2 Anatomic Sites Among a Cohort of Patients Undergoing Skin Cancer Screening.The Journal of infectious diseases · 2019Article
- Epidemiology and biology of cutaneous human papillomavirus.Clinics (Sao Paulo, Brazil) · 2018Review
- Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types.Virology · 2018Article
- Prevalence and correlates of beta human papillomavirus detection in fingernail samples from mid-adult women.Papillomavirus research (Amsterdam, Netherlands) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Accumulating evidence suggests that cutaneous human papillomavirus (HPV) infection is associated with non-melanoma skin cancer (NMSC). Little is known about the natural history of cutaneous HPV. A sub-cohort of 209 men with no NMSC history, initially enrolled in the HPV infection in men (HIM) study, were followed for a median of 12.6 months. Epidemiological data were collected through self-administered questionnaires. Cutaneous HPV DNA was measured in normal skin swabs (SS) and eyebrow hairs (EB) for 25 and 16 HPV types in genera β and γ, respectively. Any β HPV infection was more prevalent in SS (67.3%) compared to EB (56.5%, p = 0.04). Incidence in SS was higher than 20 per 1,000 person-months for HPV types 4, 5, 23, 38 and 76. Median duration of persistence of β and γ HPV infection was 8.6 and 6.1 months in EB, respectively, and 11.3 months and 6.3 months, in SS, respectively. Older age (>44 years vs. 18-30 years) was significantly associated with prevalent (SS OR = 3.0, 95% CI = 1.2-7.0) and persistent β HPV infection (EB OR = 6.1, 95% CI = 2.6-14.1). History of blistering sunburn was associated with prevalent (OR = 2.8, 95% CI = 1.3-5.8) and persistent (OR = 2.3, 95% CI = 1.2-4.6) β HPV infection in SS. Cutaneous HPV is highly prevalent in men, with age and blistering sunburn being significant risk factors for cutaneous β HPV infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.