ArticlePloS one2014
Daytime sleepiness in Parkinson's disease: a reappraisal.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015.Sleep medicine reviews · 2017Pooled it
- The Relationship Between Resting State Quantitative EEG and Daytime Sleepiness Complaints in Parkinson's Disease.Journal of sleep research · 2026Article
- Digital Technology for Sleep Symptoms in Parkinson's Disease: A Scoping Review.Journal of movement disorders · 2026Article
- Sleep Disturbances and Sexual Dysfunction in Parkinson's Disease: Sex Differences and Impact on Quality of Life in a Turkish Cohort.Journal of clinical medicine · 2026Article
- Clinical symptoms and neuroanatomical substrates of daytime sleepiness in Parkinson's disease.NPJ Parkinson's disease · 2024Article
- Sleep disorders in Parkinson's disease, an early and multiple problem.NPJ Parkinson's disease · 2024Article
- Factors correlated with excessive daytime sleepiness in patients with Parkinson's disease: A polysomnography study.Brain and behavior · 2023Article
- Sleep Architecture and Daytime Sleepiness in Patients with Erectile Dysfunction.Life (Basel, Switzerland) · 2023Article
- Analysis of sleep, daytime sleepiness, and autonomic function in multiple system atrophy and Parkinson disease: a prospective study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- Daytime sleepiness in Parkinson's disease: a multifaceted symptom.Frontiers in sleep · 2023Review
- Early onset of sleep/wake disturbances in a progressive macaque model of Parkinson's disease.Scientific reports · 2022Article
- Management of Psychiatric Disorders in Patients with Parkinson's Diseases.Indian journal of psychiatry · 2022Article
- Excessive Daytime Sleepiness in Parkinson's Disease.Nature and science of sleep · 2022Review
- Constructing prediction models for excessive daytime sleepiness by nomogram and machine learning: A large Chinese multicenter cohort study.Frontiers in aging neuroscience · 2022Article
- Mastering nocturnal jigsaws in Parkinson's disease: a dusk-to-dawn review of night-time symptoms.Journal of neural transmission (Vienna, Austria : 1996) · 2020Review
- Therapies for Restless Legs in Parkinson's Disease.Current treatment options in neurology · 2019Review
- Prevalence of sleep disorders in Parkinson's disease patients in two neurology referral hospitals in Ethiopia.BMC neurology · 2019Article
- Sleep-wake and circadian disturbances in Parkinson disease: a short clinical guide.Journal of neural transmission (Vienna, Austria : 1996) · 2019Review
- Clinical Features and Correlates of Excessive Daytime Sleepiness in Parkinson's Disease.Frontiers in neurology · 2019Article
- Excessive Daytime Sleepiness in Parkinson's Disease: Clinical Implications and Management.Chinese medical journal · 2018Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExcessive daytime sleepiness is a frequent complaint in Parkinson's disease (PD); however the frequency and risk factors for objective sleepiness remain mostly unknown. We investigated both the frequency and determinants of self-reported and objective daytime sleepiness in patients with Parkinson's disease (PD) using a wide range of potential predictors.
methodsOne hundred and thirty four consecutive patients with PD, without selection bias for sleep complaint, underwent a semi-structured clinical interview and a one night polysomnography followed by a multiple sleep latency test (MSLT). Demographic characteristics, medical history, PD course and severity, daytime sleepiness, depressive and insomnia symptoms, treatment intake, pain, restless legs syndrome, REM sleep behaviour disorder, and nighttime sleep measures were collected. Self-reported daytime sleepiness was defined by an Epworth Sleepiness Scale (ESS) score above 10. A mean sleep latency on MSLT below 8 minutes defined objective daytime sleepiness.
resultsOf 134 patients with PD, 46.3% had subjective and only 13.4% had objective sleepiness with a weak negative correlation between ESS and MSLT latency. A high body mass index (BMI) was associated with both ESS and MSLT, a pain complaint with ESS, and a higher apnea/hypopnea index with MSLT. However, no associations were found between both objective and subjective sleepiness, and measures of motor disability, disease onset, medication (type and dose), depression, insomnia, restless legs syndrome, REM sleep behaviour disorder and nighttime sleep evaluation.
conclusionWe found a high frequency of self-reported EDS in PD, a finding which is however not confirmed by the gold standard neurophysiological evaluation. Current treatment options for EDS in PD are very limited; it thus remains to be determined whether decreasing pain and BMI in association with the treatment of sleep apnea syndrome would decrease significantly daytime sleepiness in PD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.