Evidence map›Paper›PMID 25197327›Full record

ArticleTrials in vaccinology2014

Humoral and lung immune responses to Mycobacterium tuberculosis infection in a primate model of protection

Noton K Dutta, James McLachlan, Smriti Mehra, Deepak Kaushal

Abstract read
In one paragraph

Article in Trials in vaccinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Isoniazid and Rifapentine Treatment Eradicates PersistentAmerican journal of respiratory and critical care medicine · 2020
    Article
  6. Article
  7. In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control ofProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  8. Article
  9. Article
  10. Article
  11. CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Latent tuberculosis infection: myths, models, and molecular mechanisms.Microbiology and molecular biology reviews : MMBR · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Noton K Dutta *Tulane National Primate Research Center, Covington, LA, USA.
James McLachlan *Department of Microbiology & Immunology, Tulane University Health Sciences Center, New Orleans, LA, USA.
Smriti MehraTulane National Primate Research Center, Covington, LA, USA.
Deepak KaushalTulane National Primate Research Center, Covington, LA, USA.

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
ZCM:A NOVEL BROAD-SPECTRUM MICROBICIDE FOR SEXUALLY TRANSMITTED INFECTIONSP51RR000164 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI VEAZEY, RONALD S. · 1985 to 2011
$100.1M
BAA-NIH-NIAID-NCRR-DMID-03-036UC6AI058609 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI LACKNER, ANDREW A · 2003 to 2006
$21.1M
TNF AND MCP-1 IN RETROVIRUS-INDUCED BRAIN DISEASEP20RR020159 · NCRR · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI PAHAR, BAPI · 2004 to 2011
$16.1M
Genetic Requirements for the survival of Tubercle Bacilli in Nonhuman PrimatesR01AI089323 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KAUSHAL, DEEPAK · 2010 to 2014
$3.2M
Transcriptomics of Tuberculosis Latency and Reactivation in PrimatesR01HL106790 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI KAUSHAL, DEEPAK · 2010 to 2013
$3.1M
Role of miRNA in lung damage during TB and TB/AIDS Co-infectionR21AI091457 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KAUSHAL, DEEPAK · 2010 to 2011
$452k
Macaque model of TB/AIDS co-infection via natural routes of exposureR21RR026006 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI KAUSHAL, DEEPAK · 2009 to 2010
$452k
NCRR NIH HHS P20 RR020159NCRR NIH HHS P51 RR000164NCRR NIH HHS R21 RR026006NHLBI NIH HHS R01 HL106790NIAID NIH HHS R01 AI089323NIAID NIH HHS R21 AI091457NIAID NIH HHS UC6 AI058609NIH HHS P51 OD011104
6 · The paper itself

Abstract

Recently we reported (Mehra et al., 2013), that lung granulomas from

Indexed as

Animal modelBCGGranulomaLymphocyteMacrophageM. tuberculosis

Identifiers

PMID25197327
PMCPMC4153710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.