ArticleEvidence-based complementary and alternative medicine : eCAM2014
Antifungal and Antioxidant Activities of the Essential Oil from Angelica koreana Nakai.
Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Biocidal, antioxidant, and anti-inflammatory activities of essential oils extracted from Angelica spp. cultivated on contaminated soils.Scientific reports · 2025Article
- Anti-Obesity and Anti-Diabetic Effects ofInternational journal of molecular sciences · 2024Article
- Mode of Antifungal Action of Daito-Foods (Basel, Switzerland) · 2023Article
- Phytochemical Constituents, Folk Medicinal Uses, and Biological Activities of GenusMolecules (Basel, Switzerland) · 2022Review
- Phenolic compounds, essential oil composition, and antioxidant activity of Angelica purpurascens (Avé-Lall.) Gill.Turkish journal of chemistry · 2021Article
- Chemical Composition and In Vitro Antimicrobial Efficacy of Sixteen Essential Oils againstVeterinary sciences · 2018Article
- Chemical Composition and Antimicrobial Activities of the Essential Oil From Salvia mirzayanii Leaves.Journal of evidence-based complementary & alternative medicine · 2017Article
- A Review of the Composition of the Essential Oils and Biological Activities of Angelica Species.Scientia pharmaceutica · 2017Review
- Chemical Composition and Antioxidant and Antibacterial Activities of an Essential Oil Extracted from an Edible Seaweed, Laminaria japonica L.Molecules (Basel, Switzerland) · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose. The purpose of this study is to determine the antifungal and antioxidant activities of the essential oil from Angelica koreana. Methods. Essential oil was obtained from the dried roots of A. koreana by steam distillation, and its composition was identified by gas chromatography and mass spectrometry (GC-MS). The minimal inhibitory concentrations (MICs) of the oil fraction and its main components were determined by broth dilution assay using common pathogenic Aspergillus and Trichophyton species. The combined effects of the oils with itraconazole were evaluated using a checkerboard titer test. In addition, 1,1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging, nitrite inhibition, and reducing power were determined to assess the antioxidant activity of this oil. Results. The essential oil fraction and its main components showed inhibitory activity against all of the tested fungi, with minimal inhibitory concentrations (MICs) of 250-1000 μg/mL. Furthermore, this oil exhibited synergism when combined with itraconazole. Conclusion. In the treatment of infections caused by Aspergillus and Trichophyton species, combining itraconazole with either A. koreana essential oil or its main components may reduce the minimum effective dose of itraconazole required and, thus, minimize its side effects. In addition, this oil is a promising source of natural antioxidant agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.