ArticleAdvances in hematology2014
Variation of red blood cell distribution width and mean platelet volume after moderate endurance exercise.
Article in Advances in hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Red blood cell distribution width in pregnancy: a systematic review.Biochemia medica · 2018Pooled it
- Hematological, Biochemical, and Performance Adaptations in Amateur Soccer Players Following a 4-Week Preseason Training Period.Journal of functional morphology and kinesiology · 2025Article
- Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.Frontiers in neurology · 2025Article
- Single-Cell RNA Sequencing Analysis Reveals Exercise-Induced Transcriptional Dynamics in Half-Marathon Runners.Scandinavian journal of medicine & science in sports · 2025Article
- Acute Effects of Kickboxing K1 Matches on Hematological Parameters of Kickboxers.Journal of functional morphology and kinesiology · 2024Article
- Do Men and Women Differ in Hematological Adaptations to 24 Weeks of Crossfit® Training?Journal of human kinetics · 2024Article
- Red Blood Cell Distribution Width, Erythrocyte Indices, and Elongation Index at Baseline in a Group of Trained Subjects.Journal of clinical medicine · 2023Article
- Red Blood Cell Distribution Width: A Potential Inexpensive Marker for Disease Activity in Patients with Rheumatic Diseases; Scoping Review.Open access rheumatology : research and reviews · 2023Review
- Benefits on Hematological and Biochemical Parameters of a High-Intensity Interval Training Program for a Half-Marathon in Recreational Middle-Aged Women Runners.International journal of environmental research and public health · 2022Article
- Influence of chronic training workload on the hematological profile: a pilot study in sedentary people, amateur and professional cyclists.Acta bio-medica : Atenei Parmensis · 2020Article
- Athlete's Passport: Prevention of Infections, Inflammations, Injuries and Cardiovascular Diseases.Journal of clinical medicine · 2020Article
- Effects of Exercise on Chemotherapy Completion and Hospitalization Rates: The OptiTrain Breast Cancer Trial.The oncologist · 2020Article
- Red Blood Cell Distribution Width Predicts 1-month Complications after Percutaneous Transluminal Angioplasty.Journal of medical biochemistry · 2019Article
- Stability in post-seasonal hematological profiles in response to high-competitive match-play loads within elite top-level European soccer players: implications from a pilot study.Open access journal of sports medicine · 2018Article
- The Effects of Acute High-Intensity Interval Training on Hematological Parameters in Sedentary Subjects.Medical sciences (Basel, Switzerland) · 2017Article
- [Diagnostic approach to iron deficiency anemia].Wiener medizinische Wochenschrift (1946) · 2016Review
- Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome.Annals of translational medicine · 2016Article
- Learning more and spending less with neglected laboratory parameters: the paradigmatic case of red blood cell distribution width.Acta bio-medica : Atenei Parmensis · 2016Review
- Effects of Physical (In)activity on Platelet Function.BioMed research international · 2015Review
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although physical exercise strongly influences several laboratory parameters, data about the hematological changes after medium distance running are scarce. We studied 31 middle-trained athletes (mean training regimen 217 ± 32 min/week) who performed a 21.1 km, half-marathon run. Blood samples were collected before the run, at the end, and 3 and 20 hours thereafter. The complete blood count was performed on Advia 2120 and included red blood cell (RBC), reticulocyte, and platelet counts; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); reticulocyte haemoglobin content (Ret CHR); RBC distribution width (RDW), mean platelet volume (MPV). No significant variations were observed for MCH and Ret CHR. The RBC, reticulocyte, and hemoglobin values modestly decreased after the run. The MCV significantly increased at the end of running but returned to baseline 3 hours thereafter. The RDW constantly increased, reaching a peak 20 hours after the run. The platelet count and MPV both increased after the run and returned to baseline 3 hours thereafter. These results may have implications for definition of reference ranges and antidoping testing, and may also contribute to explaining the relationship between endurance exercise and mortality, since previous studies reported that RDW and MPV may be significantly associated with cardiovascular disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.