ArticleProceedings of the National Academy of Sciences of the United States of America2014
Highly sensitive detection of nanoparticles with a self-referenced and self-heterodyned whispering-gallery Raman microlaser.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 228 citations in OpenAlex.
- Single-atomic-ion detection with plasmon-enhanced whispering-gallery-mode microlasers.Nature photonics · 2026Article
- Ultrasound sensing with optical microcavities.Light, science & applications · 2024Review
- Low-Threshold Anti-Stokes Raman Microlaser on Thin-Film Lithium Niobate Chip.Materials (Basel, Switzerland) · 2024Article
- Raman Lasing in a Tellurite Microsphere with Thermo-Optical on/off Switching by an Auxiliary Laser Diode.Micromachines · 2023Article
- The missing link between standing- and traveling-wave resonators.Nanophotonics (Berlin, Germany) · 2022Article
- High-Q asymmetrically cladded silicon nitride 1D photonic crystals cavities and hybrid external cavity lasers for sensing in air and liquids.Nanophotonics (Berlin, Germany) · 2022Article
- Broadband high-Q multimode silicon concentric racetrack resonators for widely tunable Raman lasers.Nature communications · 2022Article
- Tracking Brownian motion in three dimensions and characterization of individual nanoparticles using a fiber-based high-finesse microcavity.Nature communications · 2021Article
- Single-mode characteristic of a supermode microcavity Raman laser.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- 1/f-noise-free optical sensing with an integrated heterodyne interferometer.Nature communications · 2021Article
- Review of biosensing with whispering-gallery mode lasers.Light, science & applications · 2021Review
- Optical whispering-gallery mode barcodes for high-precision and wide-range temperature measurements.Light, science & applications · 2021Article
- Induced transparency by interference or polarization.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- An Acoustic Sensor Based on Active Fiber Fabry-Pérot Microcavities.Sensors (Basel, Switzerland) · 2020Article
- Whispering-Gallery Sensors.Matter · 2020Review
- Integrated Raman Laser: A Review of the Last Two Decades.Micromachines · 2020Review
- Nonlinear Optics in Microspherical Resonators.Micromachines · 2020Review
- Reconfigurable symmetry-broken laser in a symmetric microcavity.Nature communications · 2020Article
- Parity-time symmetry and exceptional points in photonics.Nature materials · 2019Review
- On-Chip Real-Time Chemical Sensors Based on Water-Immersion-Objective Pumped Whispering-Gallery-Mode Microdisk Laser.Nanomaterials (Basel, Switzerland) · 2019Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical whispering-gallery-mode resonators (WGMRs) have emerged as promising platforms for label-free detection of nano-objects. The ultimate sensitivity of WGMRs is determined by the strength of the light-matter interaction quantified by quality factor/mode volume, Q/V, and the resolution is determined by Q. To date, to improve sensitivity and precision of detection either WGMRs have been doped with rare-earth ions to compensate losses and increase Q or plasmonic resonances have been exploited for their superior field confinement and lower V. Here, we demonstrate, for the first time to our knowledge, enhanced detection of single-nanoparticle-induced mode splitting in a silica WGMR via Raman gain-assisted loss compensation and WGM Raman microlaser. In particular, the use of the Raman microlaser provides a dopant-free, self-referenced, and self-heterodyned scheme with a detection limit ultimately determined by the thermorefractive noise. Notably, we detected and counted individual nanoparticles with polarizabilities down to 3.82 × 10(-6) μm(3) by monitoring a heterodyne beatnote signal. This level of sensitivity is achieved without exploiting plasmonic effects, external references, or active stabilization and frequency locking. Single nanoparticles are detected one at a time; however, their characterization by size or polarizability requires ensemble measurements and statistical averaging. This dopant-free scheme retains the inherited biocompatibility of silica and could find widespread use for sensing in biological media. The Raman laser and operation band of the sensor can be tailored for the specific sensing environment and the properties of the targeted materials by changing the pump laser wavelength. This scheme also opens the possibility of using intrinsic Raman or parametric gain for loss compensation in other systems where dissipation hinders progress and limits applications.
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