Evidence map›Paper›PMID 25196845›Full record

ReviewTransfusion2014

Stored red blood cell transfusions: iron, inflammation, immunity, and infection.

Steven L Spitalnik

Abstract readReview
In one paragraph

Review in Transfusion, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Duration of red blood cell storage and inflammatory marker generation.Blood transfusion = Trasfusione del sangue · 2017
    Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Steven L SpitalnikDepartment of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons-New York Presbyterian Hospital, New York, New York.

Funding

Harmful effects of red blood cell transfusions are mediated by ironR01HL115557 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPITALNIK, STEVEN L · 2013 to 2016
$2.3M
Harmful effects of transfusion of older stored red cells: iron and inflammationR01HL098014 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPITALNIK, STEVEN L · 2009 to 2012
$1.9M
Mechanisms underlying the harmful effects of stored red blood cell transfusionsK08HL103756 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOD, ELDAD ARIE · 2010 to 2014
$655k
NHLBI NIH HHS K08 HL103756NHLBI NIH HHS R01 HL098014NHLBI NIH HHS R01 HL115557NICHD NIH HHS R01 HD115557
6 · The paper itself

Abstract

Emily Cooley was a highly regarded medical technologist and morphologist. The "Emily Cooley Lectureship and Award" was established to honor her, in particular, and medical technologists, in general. This article reviews some basic concepts about the "life of a red blood cell" (RBC) and uses these to discuss the actual and potential consequences that occur in patients after clearance of transfused refrigerator storage-damaged RBCs by extravascular hemolysis.

Indexed as

Blood PreservationErythrocyte TransfusionAnimalsErythrocytesHemolysisHumansImmunityInfectionsInflammationIronIron

Identifiers

PMID25196845
PMCPMC4194176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.