Evidence map›Paper›PMID 25195788›Full record

ArticleAngewandte Chemie (International ed. in English)2014

Palladium(0)-catalyzed Heck reaction/C-H activation/amination sequence with diaziridinone: a facile approach to indolines.

Huaiji Zheng, Yingguang Zhu, Yian Shi

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Synthesis of spirooxindolesChemical science · 2023
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Synthesis of indoles, indolines, and carbazolesGreen synthesis and catalysis · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huaiji ZhengDepartment of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA).
Yingguang Zhu
Yian Shi

Funding

Diamination of OlefinsR01GM083944 · NIGMS · COLORADO STATE UNIVERSITY · PI SHI, YIAN · 2008 to 2015
$2.2M
NIGMS NIH HHS GM083944-07NIGMS NIH HHS R01 GM083944
6 · The paper itself

Abstract

Indolines are important moieties present in various biologically significant molecules and have attracted considerable attention in synthetic chemistry. This paper describes a Heck reaction/C-H activation/amination sequence for forming indolines using di-tert-butyldiaziridinone. The reaction process likely proceeds via a pallada(II)cycle, which is converted into an indoline by oxidative addition to the diaziridinone and two subsequent C-N bond formations.

Indexed as

AminationAziridinesCatalysisCyclizationIndolesOxidation-ReductionPalladiumAziridinesdi-tert-butyldiaziridinoneIndolesindolinePalladiumCH activationcyclizationheterocyclespalladiumsynthetic methods

Identifiers

PMID25195788
PMCPMC4263277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.