ArticleJournal of hepatology2015
Long-term quality of life after liver donation in the adult to adult living donor liver transplantation cohort study (A2ALL).
Article in Journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A2ALL: Adult-to-Adult Living Transplant Cohort Study
Living Donor Liver Transplantation (LDLT) in Non Resectable Colo-rectal Cancer Liver Metastasis. The LIVERMORE Trial (LIVing Donor livEr tRansplant Modena cOloRectal mEtastasis) [Original Title in Italian: "Trapianto di Fegato da Donatore Vivente Per Metastasi Epatiche Non Resecabili da Adenocarcinoma Del Colon"]
Who cites it
36 citing papers in PubMed, 99 citations in OpenAlex.
- Decision-making, regret, and quality of life in living organ donors: a cross-sectional study.Scientific reports · 2026Article
- Adaptation of living donors after liver transplantation in South Korea: an integrative review.Journal of Korean biological nursing science · 2026Article
- Examining the Relationship Between Healthy Life Awareness and Psychological Well-Being in Liver Transplantation Patients: A Structural Equation Model.Nursing & health sciences · 2025Article
- Steatosis, inflammation, fibroprogression, and cirrhosis in remnant liver post-liver donation.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Autoimmune Hepatitis on a Living Liver Donor: An Unexpected Long-Term Complication.ACG case reports journal · 2024Article
- A systematic review of the factors significantly influencing the quality of life of living liver donors.International journal of nursing sciences · 2023Review
- Does living liver donors' underestimation about surgical outcomes impact on their health-related quality of life after donation?: a descriptive cross-sectional study.Health and quality of life outcomes · 2022Article
- Postoperative Health Status and Quality of Life After Pure Laparoscopic Donor Hepatectomy for Living Donor Liver Transplantation.Annals of transplantation · 2022Article
- Evaluation of Psychosocial Outcomes of Living Liver Donors in Liver Transplantation.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Factors affecting anxiety, depression, and self-care ability in patients who have undergone liver transplantation.World journal of gastroenterology · 2021Article
- Donor quality of life after living donor liver transplantation: a review of the literature.Digestive medicine research · 2021Article
- Long-term health-related quality of life of living liver donors: what should the transplant team know?Hepatobiliary surgery and nutrition · 2021Article
- Health-related quality of life after anonymous nondirected living liver donation: A multicenter collaboration.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- [Young Adult Donor's Experiences of Living Donor Liver Transplantation].Journal of Korean Academy of Nursing · 2021Article
- Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China.Frontiers in medicine · 2021Article
- Psychosocial Outcomes of Donors Whose Recipients Died After Living Donor Liver Transplantation.Journal of gastrointestinal cancer · 2020Article
- Long-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation.The Journal of surgical research · 2020Article
- Donors' Quality of Life after Living Donor Liver Transplantation: Shiraz Organ Transplant Center Experience.International journal of organ transplantation medicine · 2020Article
- Health-related quality of life of living liver donors 1 year after donation.Hepatobiliary surgery and nutrition · 2019Article
- Long-Term Health-Related Quality of Life in Living Liver Donors.Annals of transplantation · 2019Article
Corrections and comments
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Authors and funding
14 authors at 12 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsThere are few long-term studies of the health-related quality of life (HRQOL) in living liver donors. This study aimed to characterize donor HRQOL in the Adult to Adult Living Donor Liver Transplantation Study (A2ALL) up to 11 years post-donation.
methodsBetween 2004 and 2013, HRQOL was assessed at evaluation, at 3 months, and yearly post-donation in prevalent liver donors using the short-form survey (SF-36), which provides a physical (PCS) and a mental component summary (MCS).
resultsOf the 458 donors enrolled in A2ALL, 374 (82%) had SF-36 data. Mean age at evaluation was 38 (range 18-63), 47% were male, 93% white, and 43% had a bachelor's degree or higher. MCS and PCS means were above the US population at all time points. However, at every time point there were some donors who reported poor scores (>1/2 standard deviation below the age and sex adjusted mean) (PCS: 5.3-26.8%, MCS: 10.0-25.0%). Predictors of poor PCS and MCS scores included recipient's death within the two years prior to the survey and education less than a bachelor's degree; poor PCS scores were also predicted by time since donation, Hispanic ethnicity, and at the 3-month post-donation time point.
conclusionsIn summary, most living donors maintain above average HRQOL up to 11 years prospectively, supporting the notion that living donation does not negatively affect HRQOL. However, targeted support for donors at risk for poor HRQOL may improve overall HRQOL outcomes for living liver donors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.