ArticleEarly human development2014
Auditory neural myelination is associated with early childhood language development in premature infants.
Article in Early human development, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia.American journal of obstetrics and gynecology · 2021Trial
- Auditory Brainstem Response Recorded with the NeuroAudio System in Children Under 3 Years of Age.Life (Basel, Switzerland) · 2026Article
- Comparison of Auditory Brainstem Maturation in Prematurely Born Twin and Singleton Infants: A Retrospective Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Ambient sound stimulation tunes axonal conduction velocity by regulating radial growth of myelin on an individual, axon-by-axon basis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Long-term neurodevelopmental follow-up of children exposed to pravastatin in utero.American journal of obstetrics and gynecology · 2023Article
- Effects of neurodevelopmental risk factors on brainstem maturation in premature infants.Pediatric research · 2022Article
- Neonatal brainstem auditory function associates with early receptive language development in preterm children.Acta paediatrica (Oslo, Norway : 1992) · 2020Article
- Auditory Processing Differences in Toddlers With Autism Spectrum Disorder.Journal of speech, language, and hearing research : JSLHR · 2020Article
- Developmental influence of unconjugated hyperbilirubinemia and neurobehavioral disorders.Pediatric research · 2019Review
- Bilirubin-Induced Audiologic Injury in Preterm Infants.Clinics in perinatology · 2016Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAuditory neural myelination (ANM) as evaluated by auditory brainstem evoked response (ABR) during the neonatal period has been used as a surrogate outcome for long-term neurodevelopment. The validity of ANM as a surrogate outcome for long-term neurodevelopment has not been well studied.
aimEvaluate the association of ABR I-V interpeak latency (IPL), an index of ANM, at 35 week postmenstrual age (PMA) with language outcome at 3 years of age.
designProspective study. SUBJECTS: 24-33 week gestational age (GA) infants were eligible if they did not meet exclusion criteria: craniofacial malformation, chromosomal disorders, deafness, auditory dys-synchrony, TORCH infection, or non-English speaking parents. Infants with malignancy, head injury, encephalopathy, meningitis, blindness, or who died or relocated were also excluded. OUTCOME MEASURES: ABRs were performed at 35 week PMA using 80 dB nHL and I-V IPL (ms) measured. Auditory Comprehension (AC) and Expressive Communication (EC) were evaluated by a speech-language pathologist at 3 years of age using Preschool Language Scale.
resultsEighty infants were studied. The mean GA and birth weight of infants were 29.2 weeks and 1336 g, respectively. There was association of worse ear I-V IPL and better ear I-V IPL with AC (Coefficient-5.4, 95% CI: -9.8 to -0.9 and Coefficient-5.5, 95% CI: -10 to-0.9, respectively) and EC (Coefficient-5.6, 95% CI: -9.5 to-1.8 and Coefficient-6.7, 95% CI: -10.6 to-2.7, respectively) after controlling for confounders.
conclusionThe neonatal I-V IPL is a predictor of language development at 3 years of age in preterms.
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