ArticleBMC genomics2014
Genome-wide identification of microRNA and siRNA responsive to endophytic beneficial diazotrophic bacteria in maize.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 87 citations in OpenAlex.
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- Identification of microRNAs responsive to arbuscular mycorrhizal fungi in Panicum virgatum (switchgrass).BMC genomics · 2022Article
- The Impact of Non-Nodulating Diazotrophic Bacteria in Agriculture: Understanding the Molecular Mechanisms That Benefit Crops.International journal of molecular sciences · 2022Review
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- Pi-starvation induced transcriptional changes in barley revealed by a comprehensive RNA-Seq and degradome analyses.BMC genomics · 2021Article
- Identification of miRNA-eQTLs in maize mature leaf by GWAS.BMC genomics · 2020Article
- Dynamic architecture and regulatory implications of the miRNA network underlying the response to stress in melon.RNA biology · 2020Article
- Novel insights into expansion and functional diversification of MIR169 family in tomato.Planta · 2020Article
- Deployment of Genetic and Genomic Tools Toward Gaining a Better Understanding of Rice-Frontiers in plant science · 2020Review
- Characterization and expression profiles of miRNAs in the triploid hybrids of Brassica napus and Brassica rapa.BMC genomics · 2019Article
- Defining the Genetic Basis of Plant⁻Endophytic Bacteria Interactions.International journal of molecular sciences · 2019Review
- OsmiR528 Enhances Cold Stress Tolerance by Repressing Expression of Stress Response-related Transcription Factor Genes in Plant Cells.Current genomics · 2019Article
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundSmall RNA (sRNA) has been described as a regulator of gene expression. In order to understand the role of maize sRNA (Zea mays-hybrid UENF 506-8) during association with endophytic nitrogen-fixing bacteria, we analyzed the sRNA regulated by its association with two diazotrophic bacteria, Herbaspirillum seropedicae and Azospirillum brasilense.
resultsDeep sequencing analysis was done with RNA extracted from plants inoculated with H. seropedicae, allowing the identification of miRNA and siRNA. A total of 25 conserved miRNA families and 15 novel miRNAs were identified. A dynamic regulation in response to inoculation was also observed. A hypothetical model involving copper-miRNA is proposed, emphasizing the fact that the up-regulation of miR397, miR398, miR408 and miR528, which is followed by inhibition of their targets, can facilitate association with diazotrophic bacteria. Similar expression patterns were observed in samples inoculated with A. brasilense. Moreover, novel miRNA and siRNA were classified in the Transposable Elements (TE) database, and an enrichment of siRNA aligned with TE was observed in the inoculated samples. In addition, an increase in 24-nt siRNA mapping to genes was observed, which was correlated with an increase in methylation of the coding regions and a subsequent reduction in transcription.
conclusionOur results show that maize has RNA-based silencing mechanisms that can trigger specific responses when plants interact with beneficial endophytic diazotrophic bacteria. Our findings suggest important roles for sRNA regulation in maize, and probably in other plants, during association with diazotrophic bacteria, emphasizing the up-regulation of Cu-miRNA.
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