Evidence map›Paper›PMID 25194586›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2015

The impact of hydrophobic hernia mesh coating by omega fatty acid on atraumatic fibrin sealant fixation.

S Gruber-Blum, J Brand, C Keibl, H Redl, R H Fortelny, C May, A H Petter-Puchner

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

S Gruber-BlumLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Cluster for Tissue Regeneration, Donaueschingenstrasse 13, 1200, Vienna, Austria.
J Brand
C Keibl
H Redl
R H Fortelny
C May
A H Petter-Puchner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibrin sealant (FS) is a safe and efficient fixation method in open intraperitoneal hernia repair. While favourable results have been achieved with hydrophilic meshes, hydrophobic (such as Omega fatty acid coated) meshes (OFM) have not been specifically assessed so far. Atrium C-qur lite(®) mesh was tested in rats in models of open onlay and intraperitoneal hernia repair.

methods44 meshes (2 × 2 cm) were implanted in 30 male Sprague-Dawley rats in open (n = 2 meshes per animal) and intraperitoneal technique (IPOM; n = 1 mesh per animal). Animals were randomised to four groups: onlay and IPOM sutured vs. sealed. Follow-up was 6 weeks, sutured groups serving as controls. Evaluation criteria were mesh dislocation, adhesions and foreign body reaction.

resultsFS provided a reliable fixation in onlay technique, whereas OFM meshes dislocated in the IPOM position when sealed only.

conclusionFS mesh fixation was safe with OFM meshes in open onlay repair. Intraperitoneal placement of hydrophobic meshes requires additional fixation and cannot be achieved with FS alone.

Indexed as

Coated Materials, BiocompatibleSurgical MeshWound HealingAnimalsDisease Models, AnimalFatty AcidsFibrin Tissue AdhesiveHernia, AbdominalHerniorrhaphyMaleProstheses and ImplantsRatsRats, Sprague-DawleyCoated Materials, BiocompatibleFatty AcidsFibrin Tissue Adhesive

Identifiers

PMID25194586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.