ArticleGenetics2014
Autosomal admixture levels are informative about sex bias in admixed populations.
Article in Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 33 citations in OpenAlex.
- Nested Admixture During and After the Trans-Atlantic Slave Trade on the Island of São Tomé.Molecular biology and evolution · 2025Article
- The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs.Nature communications · 2024Article
- 9,000 years of genetic continuity in southernmost Africa demonstrated at Oakhurst rockshelter.Nature ecology & evolution · 2024Article
- Counting the genetic ancestors from source populations in members of an admixed population.Genetics · 2024Article
- On the number of genealogical ancestors tracing to the source groups of an admixed population.Genetics · 2023Article
- A genetic and linguistic analysis of the admixture histories of the islands of Cabo Verde.eLife · 2023Article
- Human genetic admixture through the lens of population genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Human-Mediated Admixture and Selection Shape the Diversity on the Modern Swine (Sus scrofa) Y Chromosomes.Molecular biology and evolution · 2021Article
- Skin deep: The decoupling of genetic admixture levels from phenotypes that differed between source populations.American journal of physical anthropology · 2021Article
- Complex genetic admixture histories reconstructed with Approximate Bayesian Computation.Molecular ecology resources · 2021Article
- Genetic Consequences of the Transatlantic Slave Trade in the Americas.American journal of human genetics · 2020Article
- Assortative mating by population of origin in a mechanistic model of admixture.Theoretical population biology · 2020Article
- Exploring Cuba's population structure and demographic history using genome-wide data.Scientific reports · 2018Article
- Inference on admixture fractions in a mechanistic model of recurrent admixture.Theoretical population biology · 2018Article
- The time and place of European admixture in Ashkenazi Jewish history.PLoS genetics · 2017Article
- Ancient X chromosomes reveal contrasting sex bias in Neolithic and Bronze Age Eurasian migrations.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- Beyond 2/3 and 1/3: The Complex Signatures of Sex-Biased Admixture on the X Chromosome.Genetics · 2015Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex-biased admixture has been observed in a wide variety of admixed populations. Genetic variation in sex chromosomes and functions of quantities computed from sex chromosomes and autosomes have often been examined to infer patterns of sex-biased admixture, typically using statistical approaches that do not mechanistically model the complexity of a sex-specific history of admixture. Here, expanding on a model of Verdu and Rosenberg (2011) that did not include sex specificity, we develop a model that mechanistically examines sex-specific admixture histories. Under the model, multiple source populations contribute to an admixed population, potentially with their male and female contributions varying over time. In an admixed population descended from two source groups, we derive the moments of the distribution of the autosomal admixture fraction from a specific source population as a function of sex-specific introgression parameters and time. Considering admixture processes that are constant in time, we demonstrate that surprisingly, although the mean autosomal admixture fraction from a specific source population does not reveal a sex bias in the admixture history, the variance of autosomal admixture is informative about sex bias. Specifically, the long-term variance decreases as the sex bias from a contributing source population increases. This result can be viewed as analogous to the reduction in effective population size for populations with an unequal number of breeding males and females. Our approach suggests that it may be possible to use the effect of sex-biased admixture on autosomal DNA to assist with methods for inference of the history of complex sex-biased admixture processes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.