SynthesisThe European respiratory journal2015
Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis.
Synthesis in The European respiratory journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
138 citing papers in PubMed, 1 synthesis or guideline pooled it, 387 citations in OpenAlex.
- Exposure to long-term ambient air pollution and lung function in adults: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Effects of a Household Air Pollution Intervention with Liquefied Petroleum Gas on Cardiopulmonary Outcomes in Peru. A Randomized Controlled Trial.American journal of respiratory and critical care medicine · 2021Trial
- Trial
- Pulmonary function assessment of a community exposed to air pollution in an industrial area in Ouagadougou, Burkina Faso.Toxicology reports · 2026Article
- Air pollution from livestock farms and lung function decline in neighboring residents over 7 years.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- The effect of industry-related air pollution on pulmonary function: A prospective, cross-sectional comparative study of industrial proximity and smoking status.The Journal of international medical research · 2026Article
- TwinAIR health study: protocol for a European multi-centred, longitudinal study on indoor environmental quality (IEQ) related health and well-being.BMC public health · 2026Article
- Long-term lung function decline from chronic workplace exposure in roadside vendors of Peshawar, Pakistan.Journal of public health research · 2026Article
- Changes in lung function and fractional exhaled nitric oxide across wildfire seasons in the wildland firefighter exposure and health effect (WFFEHE) study.International journal of hygiene and environmental health · 2026Article
- New approaches to uncover COPD pathobiology and develop therapies.JCI insight · 2026Review
- Relationship between right and left ventricle function in subjects free of cardiovascular diseases: a population-based MRI study.Scientific reports · 2026Article
- Exposure-response relationship between ambient PMFrontiers in public health · 2026Article
- Interaction between genetic predisposition to successful ageing and chronic air pollution on lung disease in elderly women: results of the German SALIA cohort.BMJ open respiratory research · 2025Article
- Air pollution and depression symptoms in middle-aged and older adults in Los Angeles County.International archives of occupational and environmental health · 2025Article
- Accounting for Mobility in Air Pollution Exposure Estimates in Studies on Long-Term Health Effects.Research report (Health Effects Institute) · 2025Article
- [Spatial association between air pollutants and diseases of the respiratory and cardiovascular systems in Hamburg].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- Air Quality Index as a Predictor of Respiratory Morbidity in At-Risk Populations.International journal of environmental research and public health · 2025Article
- Assessing the impact of air pollution on lung function in South Korea using Bayesian kernel machine regression.Scientific reports · 2025Article
- Associations among air pollution, asthma and lung function: a cross-sectional study.Scientific reports · 2025Article
- Lung function may recover after coal mine fire smoke exposure: a longitudinal cohort study.BMJ open respiratory research · 2024Article
78 more citing papers are in PubMed but not listed here.
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Authors and funding
45 authors at 20 institutions in 11 countries.
Funding
Abstract
The chronic impact of ambient air pollutants on lung function in adults is not fully understood. The objective of this study was to investigate the association of long-term exposure to ambient air pollution with lung function in adult participants from five cohorts in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Residential exposure to nitrogen oxides (NO₂, NOx) and particulate matter (PM) was modelled and traffic indicators were assessed in a standardised manner. The spirometric parameters forced expiratory volume in 1 s (FEV₁) and forced vital capacity (FVC) from 7613 subjects were considered as outcomes. Cohort-specific results were combined using meta-analysis. We did not observe an association of air pollution with longitudinal change in lung function, but we observed that a 10 μg·m(-3) increase in NO₂ exposure was associated with lower levels of FEV₁ (-14.0 mL, 95% CI -25.8 to -2.1) and FVC (-14.9 mL, 95% CI -28.7 to -1.1). An increase of 10 μg·m(-3) in PM10, but not other PM metrics (PM2.5, coarse fraction of PM, PM absorbance), was associated with a lower level of FEV₁ (-44.6 mL, 95% CI -85.4 to -3.8) and FVC (-59.0 mL, 95% CI -112.3 to -5.6). The associations were particularly strong in obese persons. This study adds to the evidence for an adverse association of ambient air pollution with lung function in adults at very low levels in Europe.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.