Evidence map›Paper›PMID 25193558›Full record

ArticleCurrent treatment options in cardiovascular medicine2014

Impact of childhood obesity on cardiac structure and function.

Laurens P Koopman, Luc L Mertens

Abstract read
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In one paragraph

Article in Current treatment options in cardiovascular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  6. Impact of BMIFrontiers in pediatrics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Laurens P KoopmanDepartment of Pediatric Cardiology, ErasmusMC/Sophia Children's Hospital Rotterdam, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands, l.koopman@erasmusmc.nl.
Luc L Mertens
Erasmus MC - Sophia Children’s Hospital · NLSickKids Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementObesity prevalence is still on the rise worldwide in both adults and children. In adults, obesity is a significant cardiovascular risk factor associated with increased morbidity and mortality. In children and adolescents this is more controversial, but early changes in cardiovascular function have been observed with possible long-term implications. In this review, we focus on the cardiac impact of childhood obesity. Obese children have been shown to have larger left atrial and ventricular dimensions, and increased left ventricular mass compared to normal weight controls. In contrast to the adult population, heart failure and significant ventricular dysfunction with reduced ejection fraction has not been reported in obese children. Several studies suggest the presence of sub-clinical myocardial dysfunction with reduced tissue Doppler velocities and myocardial deformation (strain and strain rate) in obese children. These early myocardial changes are associated with a variety of risk factors, such as systemic hypertension, diabetes, and lipid abnormalities (metabolic syndrome). As the long-term effect of these early changes is uncertain, and only very limited data are available on the effect of weight reduction and lifestyle changes on myocardial functional parameters, no interventional strategies are currently recommended.

Identifiers

PMID25193558
OpenAlexW2080678818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.