Evidence map›Paper›PMID 25193248›Full record

ReviewInternational journal of STD & AIDS2015

Yaws.

Michael Marks, Dornubari Lebari, Anthony W Solomon, Stephen P Higgins

Open access · greenAbstract readReview
In one paragraph

Review in International journal of STD & AIDS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. LAMP4yaws:BMJ open · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Yaws.British medical bulletin · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Michael MarksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK The Hospital for Tropical Diseases, Mortimer Market Centre, Mortimer Market, London, UK michael.marks@lshtm.ac.uk.
Dornubari LebariDepartment of Sexual Health and HIV, North Manchester General Hospital, Manchester, UK.
Anthony W SolomonClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK The Hospital for Tropical Diseases, Mortimer Market Centre, Mortimer Market, London, UK.
Stephen P HigginsDepartment of Sexual Health and HIV, North Manchester General Hospital, Manchester, UK.
North Manchester General Hospital · GBHospital for Tropical Diseases · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Wellcome Trust 098521Wellcome Trust 102807
6 · The paper itself

Abstract

Yaws is a non-venereal endemic treponemal infection caused by Treponema pallidum sub-species pertenue, a spirochaete bacterium closely related to Treponema pallidum ssp. pallidum, the agent of venereal syphilis. Yaws is a chronic, relapsing disease predominantly affecting children living in certain tropical regions. It spreads by skin-to-skin contact and, like syphilis, occurs in distinct clinical stages. It causes lesions of the skin, mucous membranes and bones which, without treatment, can become chronic and destructive. Treponema pallidum ssp. pertenue, like its sexually-transmitted counterpart, is exquisitely sensitive to penicillin. Infection with yaws or syphilis results in reactive treponemal serology and there is no widely available test to distinguish between these infections. Thus, migration of people from yaws-endemic areas to developed countries may present clinicians with diagnostic dilemmas. We review the epidemiology, clinical presentation and treatment of yaws.

Indexed as

Anti-Bacterial AgentsFemaleHumansNeglected DiseasesPenicillin GSkinTreatment OutcomeTreponema pallidumYawsAnti-Bacterial AgentsPenicillin Gneglected tropical diseasesnon-venereal endemic syphilisSyphilisTreponema pallidum pertenueYaws

Identifiers

PMID25193248
PMCPMC4655361
OpenAlexW4247958749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.