ArticleApplied and environmental microbiology2014
Glutathione reductase-mediated synthesis of tellurium-containing nanostructures exhibiting antibacterial properties.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Microbial mechanisms to transform the super-trace element tellurium: a systematic review and discussion of nanoparticulate phases.World journal of microbiology & biotechnology · 2023Pooled it
- Statistical factorial design for optimum reduction of tellurite and production of tellurium nanostructure by a novel strain Phytobacter diazotrophicus Te1.Archives of microbiology · 2025Article
- Antimicrobial efficacy and amino acid substitutions associated with susceptibility to the tellurium compound AS101 against Haemophilus influenzae and Haemophilus parainfluenzae.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Exploring the Potential of Glutathione Reductase Overexpression to Improve Tellurium Nanoparticle Production inInternational journal of molecular sciences · 2025Article
- Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities.Amino acids · 2023Article
- Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite.Biological research · 2022Article
- Green synthesis of metalloid nanoparticles and its biological applications: A review.Frontiers in chemistry · 2022Review
- Green synthesis of biogenetic Te(0) nanoparticles by high tellurite tolerance fungusFrontiers in microbiology · 2022Article
- Article
- Tellurium: A Rare Element with Influence on Prokaryotic and Eukaryotic Biological Systems.International journal of molecular sciences · 2021Review
- Hybrid Tellurium-Lignin Nanoparticles with Enhanced Antibacterial Properties.ACS applied materials & interfaces · 2021Article
- Green Synthesis of Selenium and Tellurium Nanoparticles: Current Trends, Biological Properties and Biomedical Applications.International journal of molecular sciences · 2021Review
- Impact of Tellurite on the Metabolism ofFrontiers in microbiology · 2021Article
- In vitro biosynthesis of Ag, Au and Te-containing nanostructures by Exiguobacterium cell-free extracts.BMC biotechnology · 2020Article
- Discovery of a Novel Gene Conferring Tellurite Tolerance Through Tellurite Reduction to Escherichia coli Transformant in Marine Sediment Metagenomic Library.Marine biotechnology (New York, N.Y.) · 2019Article
- Metalloid Reductase ofACS omega · 2018Article
- Synthesis and investigations on tellurium myconanoparticles.Biotechnology reports (Amsterdam, Netherlands) · 2018Article
- Characterization of a Novel Porin-Like Protein, ExtI, from Geobacter sulfurreducens and Its Implication in the Reduction of Selenite and Tellurite.International journal of molecular sciences · 2018Article
- Synthesis and Antibacterial Activity of Metal(loid) Nanostructures by Environmental Multi-Metal(loid) Resistant Bacteria and Metal(loid)-Reducing Flavoproteins.Frontiers in microbiology · 2018Article
- Reduction of Gold (III) and Tellurium (IV) byFrontiers in microbiology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tellurium, a metalloid belonging to group 16 of the periodic table, displays very interesting physical and chemical properties and lately has attracted significant attention for its use in nanotechnology. In this context, the use of microorganisms for synthesizing nanostructures emerges as an eco-friendly and exciting approach compared to their chemical synthesis. To generate Te-containing nanostructures, bacteria enzymatically reduce tellurite to elemental tellurium. In this work, using a classic biochemical approach, we looked for a novel tellurite reductase from the Antarctic bacterium Pseudomonas sp. strain BNF22 and used it to generate tellurium-containing nanostructures. A new tellurite reductase was identified as glutathione reductase, which was subsequently overproduced in Escherichia coli. The characterization of this enzyme showed that it is an NADPH-dependent tellurite reductase, with optimum reducing activity at 30°C and pH 9.0. Finally, the enzyme was able to generate Te-containing nanostructures, about 68 nm in size, which exhibit interesting antibacterial properties against E. coli, with no apparent cytotoxicity against eukaryotic cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.