Evidence map›Paper›PMID 25192414›Full record

Trial reportBlood cancer journal2014

Long-term follow-up of serum immunoglobulin levels in blinatumomab-treated patients with minimal residual disease-positive B-precursor acute lymphoblastic leukemia.

G Zugmaier, M S Topp, S Alekar, A Viardot, H-A Horst, S Neumann, M Stelljes, R C Bargou, M Goebeler, D Wessiepe and 3 more

Open access · goldAbstract readClinical Trial, Phase IILetter
In one paragraph

Trial report in Blood cancer journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

G ZugmaierAmgen Research (Munich) GmbH, Munich, Germany.
M S Topp1] Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany [2] Comprehensive Cancer Center Mainfranken, Universitätsklinikum Würzburg, Würzburg, Germany.
S AlekarAmgen Inc., Thousand Oaks, CA, USA.
A ViardotMedical Department III, University Ulm, Ulm, Germany.
H-A HorstMedical Department II, City Hospital and University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
S NeumannMedical Department II, City Hospital and University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
M StelljesBone Marrow Transplantation Center, University Münster, Münster, Germany.
R C BargouComprehensive Cancer Center Mainfranken, Universitätsklinikum Würzburg, Würzburg, Germany.
M GoebelerComprehensive Cancer Center Mainfranken, Universitätsklinikum Würzburg, Würzburg, Germany.
D WessiepeMetronomia GmbH, Munich, Germany.
E DegenhardAmgen Research (Munich) GmbH, Munich, Germany.
N GökbugetCenter of Internal Medicine, J.W. Goethe University, Frankfurt, Germany.
M KlingerAmgen Research (Munich) GmbH, Munich, Germany.
Amgen (Germany) · DEComprehensive Cancer Center Mainfranken · DEUniversity of Lübeck · DEAmgen (United States) · USGoethe University Frankfurt · DEUniversitätsklinikum Würzburg · DEUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Precursor B-Cell Lymphoblastic Leukemia-LymphomaAntibodies, BispecificAntineoplastic AgentsFemaleFollow-Up StudiesHumansImmunoglobulinsMaleNeoplasm, ResidualAntibodies, BispecificAntineoplastic AgentsblinatumomabImmunoglobulins

Identifiers

PMID25192414
PMCPMC4183773
OpenAlexW2038139667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.