ArticleEpidemiology (Cambridge, Mass.)2014
Modification of the effect of ambient air pollution on pediatric asthma emergency visits: susceptible subpopulations.
Article in Epidemiology (Cambridge, Mass.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Chemical constituents of PMEuropean journal of pediatrics · 2025Pooled it
- Pooled it
- Short-term Effect of Fine Particulate Matter on Children's Hospital Admissions and Emergency Department Visits for Asthma: A Systematic Review and Meta-analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2016Pooled it
- Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial.The Journal of pediatrics · 2018Trial
- Determinants of volatile organic compound exposure among children with bronchopulmonary dysplasia.Pediatric research · 2026Article
- Socioeconomic disparities in mortality from indoor air pollution: A multi-country study.PloS one · 2025Article
- Outdoor Air Pollution and Pediatric Respiratory Disease.Clinics in chest medicine · 2024Review
- Ozone and childhood respiratory health: A primer for US pediatric providers and a call for a more protective standard.Pediatric pulmonology · 2023Review
- Environmental effects on acute exacerbations of respiratory diseases: A real-world big data study.The Science of the total environment · 2022Article
- Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PMEnvironmental health : a global access science source · 2021Article
- Before the First Breath: Prenatal Ultrafine Particulate Exposure and Incident Asthma.American journal of respiratory and critical care medicine · 2021Article
- Air quality, Environment and Respiratory Outcomes in Bronchopulmonary Dysplasia, the AERO-BPD cohort study: design and adaptation during the SARS-CoV-2 pandemic.BMJ open respiratory research · 2021Article
- Inferential challenges when assessing racial/ethnic health disparities in environmental research.Environmental health : a global access science source · 2021Article
- The Respiratory Risks of Ambient/Outdoor Air Pollution.Clinics in chest medicine · 2020Review
- Differential Effect of School-Based Pollution Exposure in Children With Asthma Born Prematurely.Chest · 2020Article
- Variables Associated with Emergency Department Utilization by Pediatric Patients with Asthma in a Federally Qualified Health Center.Journal of community health · 2019Article
- CC16 Levels into Adult Life Are Associated with Nitrogen Dioxide Exposure at Birth.American journal of respiratory and critical care medicine · 2019Article
- Time-series analysis of satellite-derived fine particulate matter pollution and asthma morbidity in Jackson, MS.Environmental monitoring and assessment · 2019Article
- Impacts of Regulations on Air Quality and Emergency Department Visits in the Atlanta Metropolitan Area, 1999-2013.Research report (Health Effects Institute) · 2018Article
- A prospective cohort study on ambient air pollution and respiratory morbidities including childhood asthma in adolescents from the western Cape Province: study protocol.BMC public health · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundChildren may have differing susceptibility to ambient air pollution concentrations depending on various background characteristics of the children.
methodsUsing emergency department (ED) data linked with birth records from Atlanta, Georgia, we identified ED visits for asthma or wheeze among children 2 to 16 years of age from 1 January 2002 through 30 June 2010 (n = 109,758). We stratified by preterm delivery, term low birth weight, maternal race, Medicaid status, maternal education, maternal smoking, delivery method, and history of a bronchiolitis ED visit. Population-weighted daily average concentrations were calculated for 1-hour maximum carbon monoxide and nitrogen dioxide; 8-hour maximum ozone; and 24-hour average particulate matter less than 10 microns in diameter, particulate matter less than 2.5 microns in diameter (PM2.5), and the PM2.5 components sulfate, nitrate, ammonium, elemental carbon, and organic carbon, using measurements from stationary monitors. Poisson time-series models were used to estimate rate ratios for associations between 3-day moving average pollutant concentrations and daily ED visit counts and to investigate effect-measure modification by the stratification factors.
resultsAssociations between pollutant concentrations and asthma exacerbations were larger among children born preterm and among children born to African American mothers. Stratification by race and preterm status together suggested that both factors affected susceptibility. The largest estimated effect size (for an interquartile range increase in pollution) was observed for ozone among preterm births to African American mothers: rate ratio = 1.138 (95% confidence interval = 1.077-1.203). In contrast, the rate ratio for the ozone association among full-term births to mothers of other races was 1.025 (0.970-1.083).
conclusionsResults support the hypothesis that children vary in their susceptibility to ambient air pollutants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.