ArticleJournal of occupational and environmental medicine2014
Long-term exposure to ambient air pollution and serum leptin in older adults: results from the MOBILIZE Boston study.
Article in Journal of occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Associations of Exposure to Air Pollution with Insulin Resistance: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018Pooled it
- Exposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research.International journal of environmental research and public health · 2018Pooled it
- Residential exposures associated with adiposity and proinflammatory markers in obese adults with metabolic syndrome: a cross-sectional study.Arhiv za higijenu rada i toksikologiju · 2026Article
- Exposure to air pollution is associated with adipokines in midlife women: The Study of Women's Health Across the Nation.The Science of the total environment · 2024Article
- Long-term exposure to PMThe Lancet regional health. Western Pacific · 2024Article
- Air pollution, cardiorespiratory fitness and biomarkers of oxidative status and inflammation in the 4HAIE study.Scientific reports · 2024Article
- Obesity II: Establishing causal links between chemical exposures and obesity.Biochemical pharmacology · 2022Review
- Near-roadway air pollution, immune cells and adipokines among obese young adults.Environmental health : a global access science source · 2022Article
- Article
- Associations between air pollution indicators and prevalent and incident diabetes in an African American cohort, the Jackson Heart Study.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Traffic-related air pollution is associated with glucose dysregulation, blood pressure, and oxidative stress in children.Environmental research · 2021Article
- Evaluation of associations between asthma exacerbations and distance to roadways using geocoded electronic health records data.BMC public health · 2020Article
- Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells.Particle and fibre toxicology · 2020Article
- Genetic variation, intrauterine growth, and adverse pregnancy conditions predict leptin gene DNA methylation in blood at birth and 12 months of age.International journal of obesity (2005) · 2020Article
- Air quality and obesity at older ages in China: The role of duration, severity and pollutants.PloS one · 2019Article
- Ambient air pollution exposure and obesity-related traits in Korean adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Ambient air pollution, adipokines, and glucose homeostasis: The Framingham Heart Study.Environment international · 2018Article
- Exposure to particulate matter air pollution and risk of multiple sclerosis in two large cohorts of US nurses.Environment international · 2017Article
- Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons.Neurobiology of aging · 2017Article
- Residential distance to major roadways and cardiac structure in African Americans: cross-sectional results from the Jackson Heart Study.Environmental health : a global access science source · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveLong-term exposure to traffic-related air pollution has been linked to increased risk of obesity and diabetes and may be associated with higher serum levels of the adipokine leptin, but this hypothesis has not been previously evaluated in humans.
methodsIn a cohort of older adults, we estimated the association between serum leptin concentrations and two markers of long-term exposure to traffic pollution, adjusting for participant characteristics, temporal trends, socioeconomic factors, and medical history.
resultsAn interquartile range increase (0.11 μg/m) in annual mean residential black carbon was associated with 12% (95% confidence interval: 3%, 22%) higher leptin levels. Leptin levels were not associated with residential distance to major roadway.
conclusionsIf confirmed, these findings support the emerging evidence suggesting that certain sources of traffic pollution may be associated with adverse cardiometabolic effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.