Evidence map›Paper›PMID 25191617›Full record

ArticleJournal of nutritional science2014

Effects of a beetroot juice with high neobetanin content on the early-phase insulin response in healthy volunteers.

Peter C Wootton-Beard, Kirsten Brandt, David Fell, Sarah Warner, Lisa Ryan

Abstract read
In one paragraph

Article in Journal of nutritional science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  12. Beetroot juice - a suitable post-marathon metabolic recovery supplement?Journal of the International Society of Sports Nutrition · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Biological Properties and Applications of Betalains.Molecules (Basel, Switzerland) · 2021
    Review
  17. Review
  18. Functional properties of beetroot (Nutrition & metabolism · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter C Wootton-BeardFunctional Food Centre , Oxford Brookes University , Gipsy Lane, Oxford OX3 0BP , UK.
Kirsten BrandtHuman Nutrition Research Centre, School of Agriculture and Rural Development , Newcastle University , Newcastle upon Tyne NE1 7RU , UK.
David FellCell Systems Modelling Group , Oxford Brookes University , Gipsy Lane, Oxford OX3 0BP , UK.
Sarah WarnerFunctional Food Centre , Oxford Brookes University , Gipsy Lane, Oxford OX3 0BP , UK ; Human Nutrition Research Centre, School of Agriculture and Rural Development , Newcastle University , Newcastle upon Tyne NE1 7RU , UK.
Lisa RyanFunctional Food Centre , Oxford Brookes University , Gipsy Lane, Oxford OX3 0BP , UK ; Department of Nutrition and Dietetics , Monash University , Faculty of Medicine, Nursing and Health Sciences, 264 Ferntree Gully Road, Vic 3168 , Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Produce rich in phytochemicals may alter postprandial glucose and insulin responses by interacting with the pathways that regulate glucose uptake and insulin secretion in humans. The aims of the present study were to assess the phytochemical constituents of red beetroot juice and to measure the postprandial glucose and insulin responses elicited by either 225 ml beetroot juice (BEET), a control beverage matched for macronutrient content (MCON) or a glucose beverage in healthy adults. Beetroot juice was a particularly rich source of betalain degradation compounds. The orange/yellow pigment neobetanin was measured in particularly high quantities (providing 1·3 g in the 225 ml). A total of sixteen healthy individuals were recruited, and consumed the test meals in a controlled single-blind cross-over design. Results revealed a significant lowering of the postprandial insulin response in the early phase (0-60 min) (P < 0·05) and a significantly lower glucose response in the 0-30 min phase (P < 0·05) in the BEET treatment compared with MCON. Betalains, polyphenols and dietary nitrate found in the beetroot juice may each contribute to the observed differences in the postprandial insulin concentration.

Indexed as

BEET, beetroot beverageBetalainsCHO, carbohydrateGLUC, glucose beverageiAUC, incremental AUCMCON, matched control beveragePhytochemicalsPostprandial glycaemiasAUC, segmental AUC

Identifiers

PMID25191617
PMCPMC4153083

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.