Evidence map›Paper›PMID 25191582›Full record

ArticleJournal of nutritional science2013

Children and young adults with familial hypercholesterolaemia (FH) have healthier food choices particularly with respect to dietary fat sources compared with non-FH children.

Ingunn Molven, Kjetil Retterstøl, Lene F Andersen, Marit B Veierød, Ingunn Narverud, Leiv Ose, Arne Svilaas, Margareta Wandel, Kirsten B Holven

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nutritional science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ingunn MolvenDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ; The Lipid Clinic, Oslo University Hospital , Oslo , Norway.
Kjetil RetterstølDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ; The Lipid Clinic, Oslo University Hospital , Oslo , Norway.
Lene F AndersenDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway.
Marit B VeierødDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ; Department of Biostatistics , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway.
Ingunn NarverudDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ; The Lipid Clinic, Oslo University Hospital , Oslo , Norway ; Department of Health, Nutrition and Management, Faculty of Health Sciences , Oslo and Akershus University College of Applied Sciences , Oslo , Norway.
Leiv OseDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ; The Lipid Clinic, Oslo University Hospital , Oslo , Norway.
Arne SvilaasThe Lipid Clinic, Oslo University Hospital , Oslo , Norway.
Margareta WandelDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway.
Kirsten B HolvenDepartment of Nutrition , Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway.
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial hypercholesterolaemia (FH) leads to elevated plasma levels of LDL-cholesterol and increased risk of premature atherosclerosis. Dietary treatment is recommended to all patients with FH in combination with lipid-lowering drug therapy. Little is known about how children with FH and their parents respond to dietary advice. The aim of the present study was to characterise the dietary habits in children with FH. A total of 112 children and young adults with FH and a non-FH group of children (n 36) were included. The children with FH had previously received dietary counselling. The FH subjects were grouped as: 12-14 years (FH (12-14)) and 18-28 years (FH (18-28)). Dietary data were collected by SmartDiet, a short self-instructing questionnaire on diet and lifestyle where the total score forms the basis for an overall assessment of the diet. Clinical and biochemical data were retrieved from medical records. The SmartDiet scores were significantly improved in the FH (12-14) subjects compared with the non-FH subjects (SmartDiet score of 31 v. 28, respectively). More FH (12-14) subjects compared with non-FH children consumed low-fat milk (64 v. 18 %, respectively), low-fat cheese (29 v. 3%, respectively), used margarine with highly unsaturated fat (74 v. 14 %, respectively). In all, 68 % of the FH (12-14) subjects and 55 % of the non-FH children had fish for dinner twice or more per week. The FH (18-28) subjects showed the same pattern in dietary choices as the FH (12-14) children. In contrast to the choices of low-fat dietary items, 50 % of the FH (12-14) subjects consumed sweet spreads or sweet drinks twice or more per week compared with only 21 % in the non-FH group. In conclusion, ordinary out-patient dietary counselling of children with FH seems to have a long-lasting effect, as the diet of children and young adults with FH consisted of more products that are favourable with regard to the fatty acid composition of the diet.

Indexed as

ChildrenDietDietary fat sourcesFamilial hypercholesterolaemiaFH (12–14), FH subjects aged 12 to 14 yearsFH (18–28), FH subjects aged 18 to 28 yearsFH, familial hypercholesterolaemia

Identifiers

PMID25191582
PMCPMC4153102
OpenAlexW2011695190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.