ArticleTanaffos2012
Association of obesity with asthma severity, control and quality of life.
Article in Tanaffos, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- A systematic review of psychological, physical health factors, and quality of life in adult asthma.NPJ primary care respiratory medicine · 2019Pooled it
- The Impact of Obesity on Airway Inflammation, Lung Function and Biologic Treatment in Asthma: A Narrative Review.Journal of inflammation research · 2026Review
- Review
- Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test - Impacts of body mass index.Annals of medicine · 2025Article
- High Prevalence of Uncontrolled Asthma and Its Association With Obesity and GERD-Related Symptoms in Syria: A Multicenter Cross-Sectional Study.Health science reports · 2025Article
- Association of relative fat mass with asthma: inflammatory markers as potential mediators.Lipids in health and disease · 2025Article
- Physical Health-Related Quality of Life in Relation to Mediterranean Diet Adherence in a Sample of Greek Asthma Patients: A Pilot Study.Journal of personalized medicine · 2023Article
- Do not forget asthma comorbidities in pediatric severe asthma!Frontiers in pediatrics · 2022Review
- The impact of obesity on immune function in pediatric asthma.Current opinion in allergy and clinical immunology · 2021Review
- The Management of Extrapulmonary Comorbidities and Treatable Traits; Obesity, Physical Inactivity, Anxiety, and Depression, in Adults With Asthma.Frontiers in allergy · 2021Review
- [Asthma and obesity: relationship and therapeutic implications in patients with asthma at the Department of Pneumology in Monastir, Tunisia].The Pan African medical journal · 2020Observational
- Possible risk factors for poor asthma control assessed in a cross-sectional population-based study from Telemark, Norway.PloS one · 2020Article
- Association between body mass index and asthma severity in Arab pediatric population: A retrospective study.PloS one · 2019Article
- C-reactive protein as an available biomarker determining mental component of health-related quality of life among individuals with spinal cord injury.The journal of spinal cord medicine · 2017Article
- Asthma phenotype: Clinical, physiological, and biochemical profiles of North Indian patients.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between asthma and obesity is becoming increasingly established but the mechanism that might explain the observed differences in asthma severity, control and quality of life between obese and non-obese adult asthmatics is not clear. THE PURPOSE OF THIS STUDY WAS: 1) to determine asthma severity, control and quality of life in obese asthmatics and 2) to explore, according to the body mass index (BMI), the systemic inflammatory state of asthmatic people. MATERIALS AND
methodsA cross-sectional study was conducted between 2009 and 2010. Two hundred adult asthmatic patients were included. Data analysis consisted of univariate analysis with chi-square comparison test followed by a multivariate logistic regression.
resultsObesity worsens the severity of asthma. This finding was more strongly observed among women than men. Obesity and overweight are associated with a poorer control of asthma. According to BMI, obese asthmatics had 6 times more frequent emergency visits, 5 times more frequent hospitalizations for asthma related complaints, increased missed work days and greater dose of inhaled corticosteroids (1025µg/day vs. 759µg/day of beclometasone equivalent). Mean serum level of C-reactive protein (CRP) and leptin was significantly correlated with asthma severity based on GINA classification (5.75 vs. 2.81 mg/l; 20.5 vs. 5.38 ng/ml; respectively).
conclusionIn summary, it appears that obesity is significantly associated with a greater asthma severity and a poorer asthma control and quality of life. Chronic systemic inflammation state may explain the relationship between obesity and asthma.
Indexed as
Identifiers
25191399PMC4153179W2148657942What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.