Evidence map›Paper›PMID 25191345›Full record

ArticleTanaffos2011

Evaluation of polymerase chain reaction for diagnosis of "tuberculous pleurisy".

Amir M H Asnaashari, Mohammad Towhidi, Reza Farid, Mohammad R Abbaszadegan, Davood Attaran, Seiedeh Sedigheh Fatemi, Atefeh Amiri Darban

Open access · greenAbstract read
In one paragraph

Article in Tanaffos, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Amir M H AsnaashariResearch Center of Pulmonary Diseases, Department of Pulmonology, MASHHAD-IRAN.
Mohammad TowhidiResearch Center of Pulmonary Diseases, Department of Pulmonology, MASHHAD-IRAN.
Reza FaridResearch Center of Immunology, Ghaem Hospital, Mashhad University of Medical Sciences (MUMS), MASHHAD-IRAN.
Mohammad R AbbaszadeganResearch Center of Immunology, Ghaem Hospital, Mashhad University of Medical Sciences (MUMS), MASHHAD-IRAN ; Pardis Clinical Laboratory Center, MASHHAD-IRAN.
Davood AttaranResearch Center of Pulmonary Diseases, Department of Pulmonology, MASHHAD-IRAN.
Seiedeh Sedigheh FatemiResearch Center of Pulmonary Diseases, Department of Pulmonology, MASHHAD-IRAN.
Atefeh Amiri DarbanResearch Center of Pulmonary Diseases, Department of Pulmonology, MASHHAD-IRAN.
Pulmonary Associates · USGhaem Hospital · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferential diagnosis between tuberculous pleurisy (TBP) and non- tuberculosis pleural effusion represents a critically important clinical problem. In recent years, several noninvasive methods have been found for diagnosis of tuberculous pleurisy. This study aimed to evaluate the value of detection of the genome of Mycobacterium tuberculosis (MTB) by polymerase chain reaction (PCR) method for the diagnosis of tuberculous pleurisy and compare the results with those of conventional methods. MATERIALS AND

methodsIn this cross-sectional study, we studied 62 patients (42 men and 20 women) with pleural effusion in Ghaem Hospital, affiliated to Mashhad University of Medical Sciences from January 2006 to June 2007.

resultsA total of 20 patients had tuberculous pleurisy (45.4%), 15 patients had malignant pleural effusion (34%), 3 patients had pleural effusion with various "non-tuberculosis non-malignant" etiologies (6.8%) and 6 patients had transudative pleural effusion (13.6). The sensitivity, specificity, positive predictive value and negative predictive value of PCR in tuberculous pleurisy were 85%, 100%, 100% and 88.8%, respectively.

conclusionThe value of PCR test and pleural biopsy was similar in the diagnosis of TBP. However, PCR detected MTB in pleural effusion when conventional pleural biopsy failed to do so.

Indexed as

DiagnosisPleurisyPolymerase chain reactionTuberculosis

Identifiers

PMID25191345
PMCPMC4153136
OpenAlexW2994098200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.