Evidence map›Paper›PMID 25191315›Full record

ReviewFrontiers in microbiology2014

Bifidobacterium bifidum as an example of a specialized human gut commensal.

Francesca Turroni, Sabrina Duranti, Francesca Bottacini, Simone Guglielmetti, Douwe Van Sinderen, Marco Ventura

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03952988 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of the Consumption of a Probiotic (B. Bifidum 900791)-Containing Ice-cream in Adult With Hypolactasia and Lactose Intolerance

TypeinterventionalSponsorUniversity of ChileRan2019 to 2020Enrolled50ConditionsLactose IntoleranceArmsProbiotic ice cream, Placebo ice cream
NCT07754968 narecruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of Bifidobacterium Bifidum on Symptoms of Infant Colic and Atopic Dermatitis: a Randomized Controlled Trial.

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2026 to 2028Enrolled64ConditionsInfant Colic, Atopic DermatitisArmsBifidobacterium bifidum BFP19® and BFP29® (Bifipral®), Placebo
3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

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  16. Probiotics and the intestinal tight junction barrier function.Frontiers in cell and developmental biology · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesca TurroniAlimentary Pharmabiotic Centre and Department of Microbiology, Bioscience Institute, National University of Ireland Cork, Ireland.
Sabrina DurantiLaboratory of Probiogenomics, Department of Life Sciences, University of Parma Parma, Italy.
Francesca BottaciniAlimentary Pharmabiotic Centre and Department of Microbiology, Bioscience Institute, National University of Ireland Cork, Ireland.
Simone GuglielmettiDepartment of Food, Environmental and Nutritional Sciences, University of Milan Milan, Italy.
Douwe Van SinderenAlimentary Pharmabiotic Centre and Department of Microbiology, Bioscience Institute, National University of Ireland Cork, Ireland.
Marco VenturaLaboratory of Probiogenomics, Department of Life Sciences, University of Parma Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bifidobacteria are considered dominant and for this reason key members of the human gut microbiota, particularly during the first one to two years following birth. A substantial proportion of the bifidobacterial population in the intestine of infants belong to the Bifidobacterium bifidum taxon, whose members have been shown to display remarkable physiological and genetic features involving adhesion to epithelia, as well as utilization of host-derived glycans. Here, we reviewed the current knowledge on the genetic features and associated adaptations of B. bifidum to the human gut.

Indexed as

bifidobacteriaBifidobacterium bifidumgenomicsmicrobiotaprobiotics

Identifiers

PMID25191315
PMCPMC4140077

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.