ReviewWorld journal of nuclear medicine2014
Lacrimal outflow mechanisms and the role of scintigraphy: current trends.
Review in World journal of nuclear medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 36 citations in OpenAlex.
- Evaluation of ocular surface retention of artificial tears by scintigraphy.International ophthalmology · 2026Article
- Endoscopic endonasal dacryocystorhinostomy: impact of long-standing disease on surgical outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Observational
- A bioinspired synthetic soft hydrogel for the treatment of dry eye.Bioengineering & translational medicine · 2021Article
- [Low-dose helical CT-dacryocystography in nasolacrimal duct obstruction-a prospective study].HNO · 2019Article
- Usefulness of the dacryoscintigraphy in patients with nasolacrimal duct obstruction prior to endoscopic dacryocystorhinostomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Ocular Biodistribution Studies using Molecular Imaging.Pharmaceutics · 2019Review
- Lacrimal Canaliculus Imaging Using Optical Coherence Tomography Dacryography.Scientific reports · 2018Article
- The Pre-Sac Reflux Test (PSRT): a new diagnostic test for presaccal stenosis/obstruction.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- [Treatment of nasolacrimal duct obstruction from the otorhinolaryngologist's perspective].HNO · 2016Review
- A Comprehensive Review of Dacryoscintigraphy: Part I-Indications, Techniques, and Utility.Ophthalmic plastic and reconstructive surgeryReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lacrimal outflow can be compromised by anatomical obstructions or stenoses (nonfunctional epiphora) or by defective lacrimal "pump" function (functional epiphora). Although classic imaging modalities, such as X-ray dacryocystography, computed tomography, or magnetic resonance imaging can effectively evaluate the former, their success is much less in the evaluation of the latter. This is largely due to the fact that forced diagnostic injection of fluid into the canalicular system can overcome partial obstruction sites. On the other hand, lacrimal scintigraphy mimicks "physiological" lacrimal outflow, being performed under pressure gradients present in everyday life. This is why it is considered more suitable for the study of functional epiphora. Furthermore, quantitative lacrimal scintigraphy (with time-activity curves) enables the accurate measurement of lacrimal clearance from the conjunctival fornices and may be used to study the physiology of the lacrimal "pump." Data obtained from the scintigraphic study of lacrimal outflow may be used to design more effective procedures in the management of functional and nonfunctional epiphora. This is a review article, based on a literature search with emphasis on recent publications and on those supporting interdisciplinary cooperation between ophthalmology and nuclear medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.