Evidence map›Paper›PMID 25190696›Full record

GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2014

Non-Hodgkin's lymphomas, version 4.2014.

Andrew D Zelenetz, Leo I Gordon, William G Wierda, Jeremy S Abramson, Ranjana H Advani, C Babis Andreadis, Nancy Bartlett, John C Byrd, Myron S Czuczman, Luis E Fayad and 25 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04587388 (Towards Personalized Medicine for Refractory/Relapsed Follicular Lymphoma Patients), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04587388 unknown statusnot on this mapstarted 2019, after this paper: background citation

Towards Personalized Medicine for Refractory/Relapsed Follicular Lymphoma Patients: the Cantera/Lupiae Registry

Typeobservational_patient_registrySponsorEuropean Hematology Association - Lymphoma GroupRan2019 to 2026Enrolled500ConditionsFollicular Lymphoma, Relapsed/Refractory Follicular Lymphoma
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Zanubrutinib: past, present, and future.Blood cancer journal · 2023
    Review
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  20. Journal for immunotherapy of cancer · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Andrew D Zelenetz
Leo I Gordon
William G Wierda
Jeremy S Abramson
Ranjana H Advani
C Babis Andreadis
Nancy Bartlett
John C Byrd
Myron S Czuczman
Luis E Fayad
Richard I Fisher
Martha J Glenn
Nancy Lee Harris
Richard T Hoppe
Steven M Horwitz
Christopher R Kelsey
Youn H Kim
Susan Krivacic
Ann S LaCasce
Auayporn Nademanee
Pierluigi Porcu
Oliver Press
Rachel Rabinovitch
Nishitha Reddy
Erin Reid
Ayman A Saad
Lubomir Sokol
Lode J Swinnen
Christina Tsien
Julie M Vose
Joachim Yahalom
Nadeem Zafar
Mary Dwyer
Hema Sundar
National comprehensive cancer network

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

Non-Hodgkin's lymphomas (NHL) are a heterogeneous group of lymphoproliferative disorders originating in B lymphocytes, T lymphocytes, or natural killer cells. Mantle cell lymphoma (MCL) accounts for approximately 6% of all newly diagnosed NHL cases. Radiation therapy with or without systemic therapy is a reasonable approach for the few patients who present with early-stage disease. Rituximab-based chemoimmunotherapy followed by high-dose therapy and autologous stem cell rescue (HDT/ASCR) is recommended for patients presenting with advanced-stage disease. Induction therapy followed by rituximab maintenance may provide extended disease control for those who are not candidates for HDT/ASCR. Ibrutinib, a Bruton tyrosine kinase inhibitor, was recently approved for the treatment of relapsed or refractory disease. This manuscript discusses the recommendations outlined in the NCCN Guidelines for NHL regarding the diagnosis and management of patients with MCL.

Indexed as

HumansLymphoma, Non-HodgkinNeoplasm StagingRecurrence

Identifiers

PMID25190696
PMCPMC4839265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.