ArticleDevelopmental cognitive neuroscience2014
Differentiating neural reward responsiveness in autism versus ADHD.
Article in Developmental cognitive neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Distinct neurobiological alterations during hedonic experience of rewards in attention deficit hyperactivity disorder and autism spectrum disorder: Multimodal evidence from neuroimaging meta-analyses.Molecular psychiatry · 2026Pooled it
- Comparative meta-analyses of brain structural and functional abnormalities during cognitive control in attention-deficit/hyperactivity disorder and autism spectrum disorder.Psychological medicine · 2020Pooled it
- Meta-Analysis of the RDoC Social Processing Domain across Units of Analysis in Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- Social Effort Discounting Reveals Domain-General and Social-Specific Motivation Components.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Processing of social and monetary rewards in autism spectrum disorders.The British journal of psychiatry : the journal of mental science · 2023Article
- Article
- Empathy and Anxiety in Young Girls with Fragile X Syndrome.Journal of autism and developmental disorders · 2022Article
- Discrete Wavelet Transform Analysis of the Electroretinogram in Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder.Frontiers in neuroscience · 2022Article
- Toward Precise Localization of Abnormal Brain Activity: 1D CNN on Single Voxel fMRI Time-Series.Frontiers in computational neuroscience · 2022Article
- Initial Responsiveness to Reward Attainment and Psychopathology in Children and Adults: An RDoC Study.Psychiatry research · 2020Article
- μ opioid receptor, social behaviour and autism spectrum disorder: reward matters.British journal of pharmacology · 2018Review
- Sex differences in the neural underpinnings of social and monetary incentive processing during adolescence.Cognitive, affective & behavioral neuroscience · 2018Article
- Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation.Frontiers in human neuroscience · 2018Review
- Altered reward system reactivity for personalized circumscribed interests in autism.Molecular autism · 2018Article
- Abnormal functional activation and maturation of ventromedial prefrontal cortex and cerebellum during temporal discounting in autism spectrum disorder.Human brain mapping · 2017Article
- Characterization of Face-Selective Patches in Orbitofrontal Cortex.Frontiers in human neuroscience · 2016Article
- Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors.EBioMedicine · 2015Article
- Distinct effects of ASD and ADHD symptoms on reward anticipation in participants with ADHD, their unaffected siblings and healthy controls: a cross-sectional study.Molecular autism · 2015Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although attention deficit hyperactivity disorders (ADHD) and autism spectrum disorders (ASD) share certain neurocognitive characteristics, it has been hypothesized to differentiate the two disorders based on their brain's reward responsiveness to either social or monetary reward. Thus, the present fMRI study investigated neural activation in response to both reward types in age and IQ-matched boys with ADHD versus ASD relative to typically controls (TDC). A significant group by reward type interaction effect emerged in the ventral striatum with greater activation to monetary versus social reward only in TDC, whereas subjects with ADHD responded equally strong to both reward types, and subjects with ASD showed low striatal reactivity across both reward conditions. Moreover, disorder-specific neural abnormalities were revealed, including medial prefrontal hyperactivation in response to social reward in ADHD versus ventral striatal hypoactivation in response to monetary reward in ASD. Shared dysfunction was characterized by fronto-striato-parietal hypoactivation in both clinical groups when money was at stake. Interestingly, lower neural activation within parietal circuitry was associated with higher autistic traits across the entire study sample. In sum, the present findings concur with the assumption that both ASD and ADHD display distinct and shared neural dysfunction in response to reward.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.