ArticleParasites & vectors2014
The mitochondrial genome of Parascaris univalens--implications for a "forgotten" parasite.
Article in Parasites & vectors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- First report of the complete mitochondrial genome of anInternational journal for parasitology. Parasites and wildlife · 2026Article
- Integrative evidence reveals a new species of Hysterothylacium (Nematoda: Ascaridoidea), with the characterization of its complete mitochondrial genome.International journal for parasitology. Parasites and wildlife · 2025Article
- Integrated evidence reveals a new subspecies of the genus Seuratascaris (Nematoda: Ascaridomorpha), with characterization of the complete mitochondrial genome.Parasite (Paris, France) · 2025Article
- Article
- Exploration of Parascaris species in three different Equus populations in China.Parasites & vectors · 2023Article
- The Complete Mitogenome ofAnimals : an open access journal from MDPI · 2022Article
- Equus roundworms (Parascaris univalens) are undergoing rapid divergence while genes involved in metabolic as well as anthelminic resistance are under positive selection.BMC genomics · 2022Article
- An inactivated bacterium (paraprobiotic) expressingOne health (Amsterdam, Netherlands) · 2021Article
- Parascaris spp. eggs in horses of Italy: a large-scale epidemiological analysis of the egg excretion and conditioning factors.Parasites & vectors · 2021Article
- The mitogenome of Ophidascaris wangi isolated from snakes in China.Parasitology research · 2021Article
- Human gnathostomiasis: a neglected food-borne zoonosis.Parasites & vectors · 2020Review
- Transcriptional responses in Parascaris univalens after in vitro exposure to ivermectin, pyrantel citrate and thiabendazole.Parasites & vectors · 2020Article
- Molecular characterization of β-tubulin gene associated with benzimidazole resistance in larvae of field isolates ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019Article
- Molecular identification and characterization of partial COX1 gene from caecal worm (International journal for parasitology. Parasites and wildlife · 2017Article
- Mitochondrial Phylogenomics yields Strongly Supported Hypotheses for Ascaridomorph Nematodes.Scientific reports · 2016Article
- The complete mitochondrial genome of rabbit pinworm Passalurus ambiguus: genome characterization and phylogenetic analysis.Parasitology research · 2016Article
- Transgenically expressed Parascaris P-glycoprotein-11 can modulate ivermectin susceptibility in Caenorhabditis elegans.International journal for parasitology. Drugs and drug resistance · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundParascaris univalens is an ascaridoid nematode of equids. Little is known about its epidemiology and population genetics in domestic and wild horse populations. PCR-based methods are suited to support studies in these areas, provided that reliable genetic markers are used. Recent studies have shown that mitochondrial (mt) genomic markers are applicable in such methods, but no such markers have been defined for P. univalens.
methodsMt genome regions were amplified from total genomic DNA isolated from P. univalens eggs by long-PCR and sequenced using Illumina technology. The mt genome was assembled and annotated using an established bioinformatic pipeline. Amino acid sequences inferred from all protein-encoding genes of the mt genomes were compared with those from other ascaridoid nematodes, and concatenated sequences were subjected to phylogenetic analysis by Bayesian inference.
resultsThe circular mt genome was 13,920 bp in length and contained two ribosomal RNA, 12 protein-coding and 22 transfer RNA genes, consistent with those of other ascaridoids. Phylogenetic analysis of the concatenated amino acid sequence data for the 12 mt proteins showed that P. univalens was most closely related to Ascaris lumbricoides and A. suum, to the exclusion of other ascaridoids.
conclusionsThis mt genome representing P. univalens now provides a rich source of genetic markers for future studies of the genetics and epidemiology of this parasite and its congener, P. equorum. This focus is significant, given that there is no published information on the specific prevalence and distribution of P. univalens infection in domestic and wild horse populations.
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