ArticleMedical science monitor : international medical journal of experimental and clinical research2014
Usefulness of mean platelet volume and neutrophil-to-lymphocyte ratio for evaluation of children with Familial Mediterranean fever.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Hematological Markers as Predictors of Attack and Remission Phases in Pediatric Familial Mediterranean Fever.Journal of clinical medicine · 2026Article
- Advanced biomarkers for prognostic evaluation of pneumonia severity in pediatric intensive care: focus on novel inflammatory and hematological ratios.Italian journal of pediatrics · 2025Article
- Old and New Biomarkers in Idiopathic Recurrent Acute Pericarditis (IRAP): Prognosis and Outcomes.Current cardiology reports · 2025Review
- The effectiveness of anti-interleukin-1 therapy on subclinical inflammation parameters during the attack-free period in familial Mediterranean fever patients: A case-control study.Turkish journal of medical sciences · 2022Article
- Assessment of Mean Platelet Volume in Patients with AA Amyloidosis and AA Amyloidosis Secondary to Familial Mediterranean Fever: A Retrospective Chart - Review Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Evaluation of hematological parameters in children with FMF.Clinical rheumatology · 2019Article
- New inflammatory markers in early rheumatoid arthritis.Zeitschrift fur Rheumatologie · 2018Article
- Diagnostic markers of acute infections in infants aged 1 week to 3 months: a retrospective cohort study.BMJ open · 2018Article
- Assessment of neutrophil to lymphocyte ratio and mean platelet volume in pediatric familial Mediterranean fever patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Episode of Familial Mediterranean Fever-Related Peritonitis in the Second Trimester of Pregnancy Followed by Acute Cholecystitis: Dilemmas and Pitfalls.The American journal of case reports · 2016Article
- Assessment of epicardial adipose tissue thickness and the mean platelet volume in children with familial Mediterranean fever.Italian journal of pediatrics · 2015Article
- Correlation of mean platelet volume, neutrophil-to-lymphocyte ratio, and disease activity in children with juvenile ıdiopathic arthritis.International journal of clinical and experimental medicine · 2015Article
- The relationship between red cell distribution width and homozygous M694V mutation in familial Mediterranean fever patients.Annals of Saudi medicineArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFamilial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent attacks of serositis, fever, and rash. Clinical and subclinical inflammatory processes may contribute to atherosclerosis in FMF patients, with mean platelet volume (MPV) as a potential indicator for atherosclerosis risk and neutrophil-to-lymphocyte ratio (NLR) as a marker for subclinical inflammation in these patients. In this study, we investigated whether MPV can be used as an indicator for atherosclerosis risk and if NLR is a marker for subclinical inflammation in FMF patients. MATERIAL AND
methodsThe study consisted of 75 FMF patients in attack, 157 attack-free patients, and 77 healthy controls. White blood cell count neutrophil-to-lymphocyte ratio, platelet count, MPV, PDW C-reactive protein levels, and erythrocyte sedimentation rate were recorded.
resultsThere were no significant differences between attack, attack-free, and control groups in terms of mean MPV and PDW value. NLR value was higher in the attack group. NLR value was similar in attack-free and control groups.
conclusionsWe found that MPV and PDW values are similar in FMF patients and healthy controls. NLR was higher in FMF patients in the attack period. Therefore, our results suggest that MPV and PDW values do not predict atherosclerosis risk in pediatric FMF patients, and NLR may be an indicator for attack period but not attack-free period.
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