ArticleBMC neuroscience2014
Power spectral aspects of the default mode network in schizophrenia: an MEG study.
Article in BMC neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Resting-state gamma power in schizophrenia: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers.Genes, brain, and behavior · 2015Trial
- Seeing things in psychosis: Reduced theta power in early neural responses to ambiguous visual stimuli predicts perceptual distortions.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Neuroglia's signaling: orchestrating neuronal gamma synchrony?Current opinion in neurology · 2025Review
- Resting-state EEG and MEG gamma frequencies in schizophrenia: a systematic review and exploratory power-spectrum metanalysis.Schizophrenia (Heidelberg, Germany) · 2025Review
- Indicators of Parkinsonian Visual Hallucinations: Enhanced Beta and Gamma Coherence.Noro psikiyatri arsivi · 2025Article
- Power spectral density-based resting-state EEG classification of first-episode psychosis.Scientific reports · 2024Article
- The Pathophysiological Underpinnings of Gamma-Band Alterations in Psychiatric Disorders.Life (Basel, Switzerland) · 2024Review
- Magnetoencephalography in Psychiatry: A Perspective on Translational Research and Applications.Advances in neurobiology · 2024Review
- Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Transcranial Alternating Current Stimulation (tACS) and Its Role in Schizophrenia: A Scoping Review.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- DNMT1 SNPs (rs2114724 and rs2228611) associated with positive symptoms in Chinese patients with schizophrenia.Annals of general psychiatry · 2023Article
- Article
- The Role of Alpha Oscillations among the Main Neuropsychiatric Disorders in the Adult and Developing Human Brain: Evidence from the Last 10 Years of Research.Biomedicines · 2022Review
- A review of the holy Quran listening and its neural correlation for its potential as a psycho-spiritual therapy.Heliyon · 2022Review
- Genome-wide DNA methylation in an animal model and human studies of schizophrenia: a protocol for a meta-analysis.BMJ open science · 2022Article
- Article
- Review
- Local Oscillatory Brain Dynamics of Mind Wandering in Schizophrenia.Brain sciences · 2021Article
- Overcoming Rest-Task Divide-Abnormal Temporospatial Dynamics and Its Cognition in Schizophrenia.Schizophrenia bulletin · 2021Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptoms of schizophrenia are related to deficits in self-monitoring function, which may be a consequence of irregularity in aspects of the default mode network (DMN). Schizophrenia can also be characterized by a functional abnormality of the brain activity that is reflected in the resting state. Oscillatory analysis provides an important understanding of resting brain activity. However, conventional methods using electroencephalography are restricted because of low spatial resolution, despite their excellent temporal resolution.The aim of this study was to investigate resting brain oscillation and the default mode network based on a source space in various frequency bands such as theta, alpha, beta, and gamma using magnetoencephalography. In addition, we investigated whether these resting and DMN activities could distinguish schizophrenia patients from normal controls. To do this, the power spectral density of each frequency band at rest was imaged and compared on a spatially normalized brain template in 20 patients and 20 controls.
resultsThe spatial distribution of DMN activity in the alpha band was similar to that found in previous fMRI studies. The posterior cingulate cortex (PCC) and lateral inferior parietal cortex were activated at rest, while the medial prefrontal cortex (MPFC) was deactivated at rest rather than during the task. Although the MPFC and PCC regions exhibited contrasting activation patterns, these two regions were significantly coherent at rest. The DMN and resting activities of the PCC were increased in schizophrenia patients, predominantly in the theta and alpha bands.
conclusionsBy using MEG to identify the DMN regions, predominantly in the alpha band, we found that both resting and DMN activities were augmented in the posterior cingulate in schizophrenia patients. Furthermore, schizophrenia patients exhibited decreased coherence between the PCC and MPFC in the gamma band at rest.
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