Evidence map›Paper›PMID 25189149›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015

Basic oral care for hematology-oncology patients and hematopoietic stem cell transplantation recipients: a position paper from the joint task force of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT).

Sharon Elad, Judith E Raber-Durlacher, Michael T Brennan, Deborah P Saunders, Arno P Mank, Yehuda Zadik, Barry Quinn, Joel B Epstein, Nicole M A Blijlevens, Tuomas Waltimo and 14 more

Registry-linked trialOpen access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06071637 (Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic Hematopoietic Stem Cell Transplantation.), which is not on this map. Cited by 113 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 10 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06071637 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic Hematopoietic Stem Cell Transplantation.

TypeinterventionalSponsorInstituto Nacional de Cancer, BrazilRan2023 to 2027Enrolled84ConditionsHematopoietic Stem Cell Transplantation, Low-Level Light Therapy, StomatitisArmsDouble low-power laser therapy simultaneous applicated
3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 10 syntheses or guidelines pooled it, 235 citations in OpenAlex.

  1. Pooled it
  2. MASCC/ISOO Clinical Practice Statement: management of oral complications of immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Guideline
  3. MASCC/ISOO Clinical Practice Statement: dental evaluation and management prior to treatment for hematologic malignancies and CAR T-cell therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Guideline
  4. Guideline
  5. Pooled it
  6. MASCC/ISOO clinical practice statement: Current understanding on controversies in basic oral care in hemato-oncology and hematopoietic cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Guideline
  7. MASCC/ISOO Clinical Practice Statement: Management of oral manifestations of chronic graft-versus-host-disease.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Guideline
  8. Guideline
  9. Pooled it
  10. Pooled it
  11. Tolerability and safety of a new oral device for prevention and treatment of oral mucositis in patients with hematologic malignancies undergoing chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Low-level laser therapy prevents severe oral mucositis in patients submitted to hematopoietic stem cell transplantation: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Trial
  19. Trial
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 12 countries.

Sharon EladDivision of Oral Medicine, Eastman Institute for Oral Health, University of Rochester Medical Center, 625 Elmwood Ave., Rochester, NY, 14620, USA, SElad@URMC.Rochester.edu.
Judith E Raber-Durlacher
Michael T Brennan
Deborah P Saunders
Arno P Mank
Yehuda Zadik
Barry Quinn
Joel B Epstein
Nicole M A Blijlevens
Tuomas Waltimo
Jakob R Passweg
M Elvira P Correa
Göran Dahllöf
Karin U E Garming-Legert
Richard M Logan
Carin M J Potting
Michael Y Shapira
Yoshihiko Soga
Jacqui Stringer
Monique A Stokman
Samuel Vokurka
Elisabeth Wallhult
Noam Yarom
Siri Beier Jensen
Hebrew University of Jerusalem · ILKarolinska Institutet · SERadboud University Medical Center · NLAcademic Medical Center · NLCarolinas Medical Center · USCity of Hope · USEastman Chemical Company (United States) · USHealth Sciences North · CAOkayama University Hospital · JPSahlgrenska University Hospital · SESheba Medical Center · ILThe Christie Hospital · GBUniversidade Estadual de Campinas (UNICAMP) · BRUniversity Hospital of Basel · CHUniversity Hospital Plzen · CZUniversity of Adelaide · AUUniversity of Amsterdam · NLUniversity of Basel · CHUniversity of Copenhagen · DKUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHematology-oncology patients undergoing chemotherapy and hematopoietic stem cell transplantation (HSCT) recipients are at risk for oral complications which may cause significant morbidity and a potential risk of mortality. This emphasizes the importance of basic oral care prior to, during and following chemotherapy/HSCT. While scientific evidence is available to support some of the clinical practices used to manage the oral complications, expert opinion is needed to shape the current optimal protocols.

methodsThis position paper was developed by members of the Oral Care Study Group, Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT) in attempt to provide guidance to the health care providers managing these patient populations.

resultsThe protocol on basic oral care outlined in this position paper is presented based on the following principles: prevention of infections, pain control, maintaining oral function, the interplay with managing oral complications of cancer treatment and improving quality of life.

conclusionUsing these fundamental elements, we developed a protocol to assist the health care provider and present a practical approach for basic oral care. Research is warranted to provide robust scientific evidence and to enhance this clinical protocol.

Indexed as

Dental CareOral HealthOral HygieneBone MarrowBone Marrow CellsBone Marrow TransplantationClinical ProtocolsFemaleHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansMalePain ManagementQuality of Life

Identifiers

PMID25189149
PMCPMC4328129
OpenAlexW2125101967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.