Evidence map›Paper›PMID 25188537›Full record

ArticleJAMA dermatology2015

Cidofovir gel as treatment of follicular spicules in multiple myeloma.

Sander van Boheemen, Terry Jones, Barbara Muhlemann, Mariet C Feltkamp, Ron A M Fouchier, Enes Hajdarbegovic

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in JAMA dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sander van BoheemenDepartment of Viroscience, Erasmus Medical Centre, Rotterdam, the Netherlands.
Terry JonesCenter for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, England.
Barbara MuhlemannCenter for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, England.
Mariet C FeltkampDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands.
Ron A M FouchierDepartment of Viroscience, Erasmus Medical Centre, Rotterdam, the Netherlands.
Enes HajdarbegovicDepartment of Dermatology and Venereology, Erasmus Medical Centre, Rotterdam, the Netherlands.
Erasmus University Rotterdam · NLUniversity of Cambridge · GBLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceThe cause of follicular spicules in multiple myeloma (MM) is not known. OBSERVATIONS: We present a case of follicular spicules in a patient with MM, which is very reminiscent of trichodysplasia spinulosa caused by a polyomavirus. No trichodysplasia spinulosa-associated polyomavirus could be isolated from the skin lesions; however, the spicules were positive for Merkel cell carcinoma virus, which is also a polyomavirus. CONCLUSIONS AND RELEVANCE: Follicular spicules in MM are probably not caused by the trichodysplasia spinulosa-associated virus. Merkel cell polyomavirus could contribute to the origin of this dermatosis.

Indexed as

AgedAntiviral AgentsCarcinoma, Merkel CellCidofovirCytosineGelsHair FollicleHumansMaleMerkel cell polyomavirusMultiple MyelomaOrganophosphonatesPolyomavirus InfectionsSkin NeoplasmsAntiviral AgentsCidofovirCytosineGelsOrganophosphonates

Identifiers

PMID25188537
OpenAlexW2042943242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.