ArticlePLoS neglected tropical diseases2014
A cross-sectional serological study of cysticercosis, schistosomiasis, toxocariasis and echinococcosis in HIV-1 infected people in Beira, Mozambique.
Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The epidemiology of human Taenia solium infections: A systematic review of the distribution in Eastern and Southern Africa.PLoS neglected tropical diseases · 2023Pooled it
- Africa-wide meta-analysis on the prevalence and distribution of human cystic echinococcosis and canine Echinococcus granulosus infections.Parasites & vectors · 2022Pooled it
- Association of schistosomiasis and HIV infections: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Present Situation of Cystic Echinococcosis in Africa: A Narrative Review.Veterinary sciences · 2026Review
- Imaging comparisons of cystic echinococcosis in HIV-positive and HIV-negative patients.SA journal of radiology · 2026Article
- Diagnostic Accuracy of Antigen ELISA and Western Blot IgG for Neurocysticercosis in People Living with HIV/AIDS in Tanzania.Tropical medicine and infectious disease · 2025Article
- Cysticercosis and neurocysticercosis in people from Mocuba district, Zambézia province: A Mozambican community-based study.PLoS neglected tropical diseases · 2025Article
- Knowledge, attitudes, and perception of dog owners on the transmission, control and prevention of cystic echinococcosis and other gastrointestinal parasites in dogs of Southern provinces of Mozambique.BMC veterinary research · 2025Article
- Seroprevalence and Risk Factors forResearch and reports in tropical medicine · 2025Article
- Cytokine profiles and CD4 counts in HIV-positive individuals with cysticercosis: implications for sex-specific immune responses in co-endemic regions of Tanzania.Frontiers in immunology · 2025Article
- A Cross Sectional Study on the Bidirectional Interactions Between Leptospirosis and HIV Infection Among Patients from Maputo Central Hospital, Mozambique.Research and reports in tropical medicine · 2024Article
- Who Let the Dogs Out? Unmasking the Neglected: A Semi-Systematic Review on the Enduring Impact of Toxocariasis, a Prevalent Zoonotic Infection.International journal of environmental research and public health · 2023Review
- Molecular investigation of Toxocara infection from the serum of people living with HIV in Alborz, Iran.BMC infectious diseases · 2023Article
- Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil.Parasites & vectors · 2022Article
- HIV and Mediterranean Zoonoses: A Review of the Literature.Infectious disease reports · 2022Review
- The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique.PLoS neglected tropical diseases · 2022Article
- Prevalence and molecular characterization of cystic hydatidosis in livestock slaughtered in southern Mozambique.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- A case and literature review of intraocular echinococcus causing bilateral visual loss in a HIV-infected patient.SAGE open medical case reports · 2022Article
- Human Toxocariasis in individuals with blood disorders and cancer patients: the first seroepidemiological study in Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Neurocysticercosis in Epileptic Children: An Overlooked Condition in Mozambique, Challenges in Diagnosis, Management and Research Priorities.EC microbiology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundHelminthic infections are highly endemic in Mozambique, due to limited access to healthcare and resources for disease prevention. Data on the subclinical prevalence of these diseases are scarce due to the fact that an immunological and imaging diagnosis is not often available in endemic areas. We conducted a cross-sectional study on HIV1(+) patients from Beira city in order to determine the seroprevalence of cysticercosis, schistosomiasis, toxocariasis and echinoccocosis and its possible interaction with HIV infection. METHODOLOGY/PRINCIPAL
findingsPatients (601) were voluntarily recruited at the Ponta Gea Health Center and their demographic and clinical data were recorded (including CD4(+) cell count and antiretroviral regimen). Mean age was 39.7 years, 378 (62.9%) were women and 223 (37.1%) were men. Four hundred seventy-five (475) patients (79%) were already on highly active antiretroviral therapy (HAART), and 90 started therapy after being enrolled in the study. For serological testing we used a Multiplex Western Blot IgG from LDBIO Diagnostics. The overall seroprevalence was 10.2% for cysticercosis, 23% for schistosomiasis, 7.3% for toxocariasis and 17.3% for echinococcosis. CONCLUSIONS/SIGNIFICANCE: Neither age nor the CD4(+) count were significantly associated with the seroprevalence of the helminths studied. However, patients with CD4(+) between 200-500/µl had a higher seroprevalence to all helminths than those with less than 200/µl cells/and those with more than 500 cells/µl. Female gender was significantly associated with cysticercosis and schistosomiasis, and being in HAART with toxocariasis. Headache was significantly associated with cysticercosis and toxocariasis. There was no association between epilepsy and seropositivity to any of the parasites. The study concluded that a clear understanding of the prevalence and manifestations of these coinfections, how best to diagnose subclinical cases, and how to manage diseases with concomitant antiretroviral therapy is needed.
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