ReviewNeuropsychiatric disease and treatment2014
Diagnostic and therapeutic utility of neuroimaging in depression: an overview.
Review in Neuropsychiatric disease and treatment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 6 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Seed-based resting-state connectivity as a neurosignature in fibromyalgia and depression: a narrative systematic review.Frontiers in human neuroscience · 2025Pooled it
- Structural and functional features of treatment-resistant depression: A systematic review and exploratory coordinate-based meta-analysis of neuroimaging studies.Psychiatry and clinical neurosciences · 2023Pooled it
- Shared and distinct brain fMRI response during performance of working memory tasks in adult patients with schizophrenia and major depressive disorder.Human brain mapping · 2021Pooled it
- Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety.Neuroscience and biobehavioral reviews · 2018Pooled it
- Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis.Molecular psychiatry · 2017Pooled it
- Computational meta-analysis of statistical parametric maps in major depression.Human brain mapping · 2016Pooled it
- Baseline Functional Connectivity in Resting State Networks Associated with Depression and Remission Status after 16 Weeks of Pharmacotherapy: A CAN-BIND Report.Cerebral cortex (New York, N.Y. : 1991) · 2022Trial
- Prefrontal networks dynamically related to recovery from major depressive disorder: a longitudinal pharmacological fMRI study.Translational psychiatry · 2019Trial
- The effects of serotonin modulation on medial prefrontal connectivity strength and stability: A pharmacological fMRI study with citalopram.Progress in neuro-psychopharmacology & biological psychiatry · 2018Trial
- Speech as a biomarker for supported diagnosis of major depressive disorder using self-supervised representations.Nature communications · 2026Article
- Subjective cognitive decline in major depressive patients is associated with altered entropy and connectivity changes of temporal and insular region.Translational psychiatry · 2025Article
- Machine learning models predict the emergence of depression in Argentinean college students during periods of COVID-19 quarantine.Frontiers in psychiatry · 2024Article
- Serum Extracellular Vesicle-Derived hsa-miR-2277-3p and hsa-miR-6813-3p Are Potential Biomarkers for Major Depression: A Preliminary Study.International journal of molecular sciences · 2023Article
- An integrated precision medicine approach in major depressive disorder: a study protocol to create a new algorithm for the prediction of treatment response.Frontiers in psychiatry · 2023Article
- Imaging correlates of depression in progressive supranuclear palsy.Journal of neurology · 2022Article
- The Interplay of Environmental Exposures and Mental Health: Setting an Agenda.Environmental health perspectives · 2022Review
- Update on GPCR-based targets for the development of novel antidepressants.Molecular psychiatry · 2022Review
- Editorial: Use of neuroimaging techniques for the prevention, assessment, and treatment of mood disorders.Frontiers in psychiatry · 2022Article
- Correlation Between Serum High-Sensitivity C-Reactive Protein, Tumor Necrosis Factor-Alpha, Serum Interleukin-6 and White Matter Integrity Before and After the Treatment of Drug-Naïve Patients With Major Depressive Disorder.Frontiers in neuroscience · 2022Article
- Editorial: Novel Approaches to Improve Detection, Differentiation and Treatment in Mood Disorders.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A growing number of studies have used neuroimaging to further our understanding of how brain structure and function are altered in major depression. More recently, these techniques have begun to show promise for the diagnosis and treatment of depression, both as aids to conventional methods and as methods in their own right. In this review, we describe recent neuroimaging findings in the field that might aid diagnosis and improve treatment accuracy. Overall, major depression is associated with numerous structural and functional differences in neural systems involved in emotion processing and mood regulation. Furthermore, several studies have shown that the structure and function of these systems is changed by pharmacological and psychological treatments of the condition and that these changes in candidate brain regions might predict clinical response. More recently, "machine learning" methods have used neuroimaging data to categorize individual patients according to their diagnostic status and predict treatment response. Despite being mostly limited to group-level comparisons at present, with the introduction of new methods and more naturalistic studies, neuroimaging has the potential to become part of the clinical armamentarium and may improve diagnostic accuracy and inform treatment choice at the patient level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.