Evidence map›Paper›PMID 25187700›Full record

ArticleClinical interventions in aging2014

Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report.

Licia Manzon, Evaristo Ettorre, Giovanni Viscogliosi, Stefano Ippoliti, Fabio Filiaci, Claudio Ungari, Giovanni Fratto, Alessandro Agrillo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Rheumatoid arthritis complicated with cervical actinomycosis and ureteral obstruction: A case report and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Experience of pain in a patient with BRONJ.Clinical interventions in aging · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Licia ManzonDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Rome, Italy.
Evaristo EttorreDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Rome, Italy.
Giovanni ViscogliosiDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Rome, Italy.
Stefano IppolitiDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Rome, Italy.
Fabio FiliaciDepartment of Odontology and Maxillofacial Surgery, "Sapienza" University, Rome, Italy.
Claudio UngariDepartment of Odontology and Maxillofacial Surgery, "Sapienza" University, Rome, Italy.
Giovanni FrattoDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Rome, Italy.
Alessandro AgrilloDepartment of Odontology and Maxillofacial Surgery, "Sapienza" University, Rome, Italy.
CTO Andrea Alesini · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely associated with BRONJ. Instead, the risk greatly increases whether the patient is concomitantly taking steroid and/or immunosuppressant agents. The aims of this paper are to briefly discuss the evidence of the associations between bisphosphonate therapy and BRONJ, and the effects of co-occurring factors such as the presence of rheumatoid arthritis, dental surgery, and concomitant corticosteroid therapy. In particular, we present the case of an elderly woman with BRONJ suffering from rheumatoid arthritis, with a recent dental extraction and with a very unusual complication: a temporal abscess, who was successfully treated.

Indexed as

AbscessAgedAnti-Bacterial AgentsArthritis, RheumatoidBisphosphonate-Associated Osteonecrosis of the JawDiagnosis, DifferentialFemaleHumansMandibular DiseasesRadiography, PanoramicTomography, X-Ray ComputedAnti-Bacterial Agentsadverse reactionbisphosphonate-related osteonecrosis of the jawBRONJsteroids

Identifiers

PMID25187700
PMCPMC4149335
OpenAlexW2082598572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.