Evidence map›Paper›PMID 25187682›Full record

ArticleBioinformation2014

MiR-3960 binding sites with mRNA of human genes.

Anatoly Ivashchenko, Olga Berillo, Anna Pyrkova, Raigul Niyazova, Shara Atambayeva

Open access · hybridAbstract read
In one paragraph

Article in Bioinformation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. In Silico Analysis of miRNA-mRNA Binding Sites inPlants (Basel, Switzerland) · 2025
    Article
  5. An Overview of miRNA and miRNA Target Analysis Tools.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  6. Article
  7. Article
  8. In Silico Study of piRNA Interactions with the SARS-CoV-2 Genome.International journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Frontiers in genetics · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anatoly IvashchenkoNational Nanotechnology Laboratory, al-Farabi Kazakh National University, Almaty-050038, Kazakhstan.
Olga BerilloNational Nanotechnology Laboratory, al-Farabi Kazakh National University, Almaty-050038, Kazakhstan.
Anna PyrkovaNational Nanotechnology Laboratory, al-Farabi Kazakh National University, Almaty-050038, Kazakhstan.
Raigul NiyazovaNational Nanotechnology Laboratory, al-Farabi Kazakh National University, Almaty-050038, Kazakhstan.
Shara AtambayevaNational Nanotechnology Laboratory, al-Farabi Kazakh National University, Almaty-050038, Kazakhstan.
Al-Farabi Kazakh National University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of miRNA in cellular regulation is gaining momentum. Therefore, it is of interest to study miRNA in human genes. Hence, the humanmRNA sequences (12,175) were searched for miRNA binding sites and 2,563predicted sites were found. We observed that the miR-3960 has more than 1000mRNA binding sites with high affinity (with ΔG/ΔGm values greater than or equal to 90%) for 375genes. The miR-3960 has 565 binding sites in the 5'UTRs and 515 sites in theCDS of mRNAs. Nucleotide sequences of the binding sites in CDS encode for polyalanine orpolyproline. It is observed that miR-3960 has binding sites in 73 mRNAs of target genesencoded transcription factors. Thus, we document predictedproperties (polysites, sites in CDS) of uncharacterized miR-3960 binding sites. The studying of the miRNA properties is important for creation of diagnostic methods of cancer.

Indexed as

GenesMicroRNAmiR-3960mRNA

Identifiers

PMID25187682
PMCPMC4135290
OpenAlexW1975855260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.