Evidence map›Paper›PMID 25187638›Full record

ArticleJournal of clinical microbiology2014

First reported case of Ehrlichia ewingii involving human bone marrow.

M Brandon Allen, Bobbi S Pritt, Lynne M Sloan, Christopher D Paddock, Chaitanya K Musham, Jeanette M Ramos, Neslihan Cetin, Eric R Rosenbaum

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

M Brandon AllenDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Bobbi S PrittDepartment of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Lynne M SloanDepartment of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Christopher D PaddockInfectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Chaitanya K MushamDepartment of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Jeanette M RamosDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Neslihan CetinDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Eric R RosenbaumDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA errosenbaum@uams.edu.
University of Arkansas for Medical Sciences · USMayo Clinic · USCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old female with a history of multiple tick bites presented with fever and pancytopenia. Intracytoplasmic rickettsial morulae were detected on peripheral smear and bone marrow biopsy specimens, and PCR amplified Ehrlichia ewingii DNA from both specimens. To our knowledge, this is the first report of E. ewingii infection of human bone marrow.

Indexed as

AgedBloodBone MarrowDNA, BacterialEhrlichiaEhrlichiosisFemaleGranulocytesHumansMicroscopyOsteomyelitisPolymerase Chain ReactionTick BitesDNA, Bacterial

Identifiers

PMID25187638
PMCPMC4313272
OpenAlexW2150002684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.