ArticleJournal of hypertension2014
Are personality traits associated with white-coat and masked hypertension?
Article in Journal of hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Pooled it
- White-coat hypertension is a risk factor for cardiovascular diseases and total mortality.Journal of hypertension · 2017Pooled it
- Association Between Symptoms of Anxiety and Depression and Blood Pressure Variability in Older Outpatients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Observational
- Autonomic cardiovascular mechanisms linked to stress in dental practice.British dental journal · 2026Review
- Blood pressure and vascular function response to maximal graded exercise tests in young men with masked hypertension.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- A Metric Shedding Light on the Relationship Between White Coat Hypertension and Anxiety: The Hospital Anxiety and Depression Scale-Anxiety.Anatolian journal of cardiology · 2024Article
- The association between depressive symptoms and masked hypertension in participants with normotension measured at research center.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- The Influence of Factors such as Anxiety on the White Coat Effect during the Treatment of Patients with Hypertension.Reviews in cardiovascular medicine · 2022Article
- Depression and anxiety in different hypertension phenotypes: a cross-sectional study.Annals of general psychiatry · 2022Article
- The effect of daily life activities on intraocular pressure related variations in open-angle glaucoma.Scientific reports · 2021Article
- Masked Uncontrolled Hypertension Is Accompanied by Increased Out-of-Clinic Aldosterone Secretion.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Evaluation of affective temperaments and arterial stiffness in different hypertension phenotypes.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Acute emotional stress as a trigger for intraocular pressure elevation in Glaucoma.BMC ophthalmology · 2019Article
- Personality Traits, Clinical Characteristics, and Health-Related Quality of Life of Patients with Hypertension in a Primary Hospital in Ghana.International journal of hypertension · 2019Article
- White coat syndrome and its variations: differences and clinical impact.Integrated blood pressure control · 2018Review
- Gender specific profiles of white coat and masked hypertension impacts on arterial structure and function in the SardiNIA study.International journal of cardiology · 2016Article
- The nocebo effect of drugs.Pharmacology research & perspectives · 2016Article
- Dysregulated Blood Pressure: Can Regulating Emotions Help?Current hypertension reports · 2015Review
- Impact of depression on masked hypertension and variability in home blood pressure in treated hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Article
- Current status of white coat hypertension: where are we?Therapeutic advances in cardiovascular diseaseReview
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesAnxiety and other psychological dispositions are thought to be associated with blood pressure. This study tests whether personality traits have long-term associations with masked and white-coat effects.
methodsA community-based sample of 2838 adults from Sardinia (Italy) completed the Revised NEO Personality Inventory, and 7 years later, blood pressure was assessed in the clinic and with ambulatory monitoring. Logistic regressions were used to test whether anxiety, neuroticism, extraversion, openness, agreeableness, and conscientiousness predicted the white-coat and masked hypertension phenomena. Age, sex, and antihypertensive medication use were tested as moderators.
resultsSignificant interactions were found between personality traits and antihypertensive medications in predicting masked and white-coat effects. Only among those taking antihypertensive medication, higher anxiety was associated with a higher risk of pseudo-resistant hypertension due to white-coat effect (odds ratio 1.39, 95% confidence interval 1.01-1.91) and higher conscientiousness was associated with a lower risk of masked uncontrolled hypertension (odds ratio 0.70, 95% confidence interval 0.49-0.99). There were no significant interactions with age or sex.
conclusionsAmong those on antihypertensive medications, anxious individuals were more likely to have pseudo-resistant hypertension due to white-coat effect and less conscientious individuals were at increased risk of masked uncontrolled hypertension. Particularly among anxious and less conscientious individuals, ambulatory monitoring may improve the tailoring of pharmacological treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.