Evidence map›Paper›PMID 25186339›Full record

SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2014

Diagnostic yield of computed tomography scan for pediatric hearing loss: a systematic review.

Jenny X Chen, Bart Kachniarz, Jennifer J Shin

Abstract readSystematic Review
In one paragraph

Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Diagnostic yield of MRI for pediatric hearing loss: a systematic review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2015
    Pooled it
  2. Guideline
  3. Patient-Centered Approach to Assessing Voice Impairment.JAMA otolaryngology-- head & neck surgery · 2025
    Article
  4. Article
  5. Review
  6. [Computer tomography demonstrations of single-sided deafness].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  7. A proposal for comprehensive newborn hearing screening to improve identification of deaf and hard-of-hearing children.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Article
  8. Article
  9. Diagnosis and Management of Congenital Sensorineural Hearing Loss.Current treatment options in pediatrics · 2016
    Article
  10. Does an Otolaryngology-Specific Database Have Added Value? A Comparative Feasibility Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2016
    Article
  11. Sensorineural Hearing Loss: A Changing Paradigm for Its Evaluation.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2015
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jenny X ChenHarvard Medical School, Boston, Massachusetts, USA.
Bart KachniarzHarvard Medical School, Boston, Massachusetts, USA.
Jennifer J ShinHarvard Medical School, Boston, Massachusetts, USA jennifer_shin@meei.harvard.edu.

Funding

The CHEER NetworkU24DC012206 · NIDCD · DUKE UNIVERSITY · PI WITSELL, DAVID L · 2012 to 2016
$4.1M
NIDCD NIH HHS U24 DC012206
6 · The paper itself

Abstract

backgroundComputed tomography (CT) has been used in the assessment of pediatric hearing loss, but concern regarding radiation risk and increased utilization of magnetic resonance imaging (MRI) have prompted us toward a more quantitative and sophisticated understanding of CT's potential diagnostic yield.

objectiveTo perform a systematic review to analyze the diagnostic yield of CT for pediatric hearing loss, including subgroup evaluation according to impairment severity and laterality, as well as the specific findings of enlarged vestibular aqueduct and narrow cochlear nerve canal. DATA SOURCES: PubMed, EMBASE, and the Cochrane Library were assessed from the date of their inception to December 2013. In addition, manual searches of bibliographies were performed and topic experts were contacted. REVIEW

methodsData from studies describing the use of CT in the diagnostic evaluation of pediatric patients with hearing loss of unknown etiology were evaluated, according to a priori inclusion/exclusion criteria. Two independent evaluators corroborated the extracted data. Heterogeneity was evaluated according to the I(2) statistic.

resultsIn 50 criteria-meeting studies, the overall diagnostic yield of CT ranged from 7% to 74%, with the strongest and aggregate data demonstrating a point estimate of 30%. This estimate corresponded to a number needed to image of 4 (range, 2-15). The most commonly identified findings were enlarged vestibular aqueduct and cochlear anomalies. The largest studies showed a 4% to 7% yield for narrow cochlear nerve canal.

conclusionThese data, along with similar analyses of radiation risk and risks/benefits of sedated MRI, may be used to help guide the choice of diagnostic imaging.

Indexed as

Tomography, X-Ray ComputedChildHearing LossHumansadolescentchildcomputed tomographydiagnosishearing lossimaginginfantpediatricsystematic review

Identifiers

PMID25186339
PMCPMC4465545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.