Evidence map›Paper›PMID 25185945›Full record

ArticleCell metabolism2014

When autophagy chaperones liver metabolism.

Patrice Codogno, Sophie Lotersztajn

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Patrice CodognoINSERM U1151-CNRS UMR 8253, Institut Necker Enfants-Malades (INEM), 75014 Paris, France; Université Paris Descartes-Sorbonne Paris Cité, 70014 Paris, France. Electronic address: patrice.codogno@inserm.fr.
Sophie LotersztajnINSERM U1149, Center for research on Inflammation, 75018 Paris, France; Université Paris Diderot-Sorbonne Paris Cité, Faculté de Médecine, Site Xavier Bichat, 75018 Paris, France. Electronic address: sophie.lotersztajn@inserm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaperone-mediated autophagy (CMA) governs degradation of cytosolic proteins damaged by nutritional changes and declines with age. In this issue, Schneider et al. (2014) reveal CMA as a novel player in the regulation of liver lipid and carbohydrate metabolism and suggest that defects in CMA may play a major role in metabolic dysregulation.

Indexed as

AutophagyAnimalsFatty LiverFemaleLiverLysosomal-Associated Membrane Protein 2MaleLysosomal-Associated Membrane Protein 2

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.